Osteoarthritis: MR imaging findings in different stages of disease and correlation with clinical findings
Osteoarthritis: MR imaging findings in different stages of disease and correlation with clinical findings
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DOI：
10.1148/radiol.2262012190
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发表时间：
2003-02-01
期刊：
影响因子：
19.7
通讯作者：
Majumdar, S
中科院分区：
文献类型：
--
作者：
Link, TM;Steinbach, LS;Majumdar, S
目得：为了确定是否膝关节疼痛，僵硬，和有限的功能，在不同阶段的骨关节炎患者与疾病的程度进行评估的磁共振（MR）图像和X线片.MATERIALS AND METHODS：在50例不同程度的膝关节炎患者的X线片进行了评估，通过使用西安大略和麦克马斯特大学（WOMAC）骨关节炎指数和Keligren-劳伦斯（KL）规模。MR图像获得和分析的软骨病变，骨髓水肿的模式，韧带和adjacent lesions.RESULTS：13 16个膝关节KL评分为4显示全层软骨病变和骨髓水肿的模式。KL评分为3分的12例膝关节中有5例发现交叉韧带撕裂，KL评分为4分的16例膝关节中有9例发现交叉韧带撕裂。虽然KL评分与软骨病变分级显著相关（P <0.05），并且在MR图像上发现KL评分较高的病变百分比显著较高，但MR成像结果与KL评分与临床结果之间的相关性不显著（P > 0.05）。WOMAC评分仅在软骨病变分级上有显著性差异（P <0.05）。结论：晚期骨关节炎患者的MRI图像常显示软骨病变、骨髓水肿模式、关节和韧带病变。临床表现与KL评分和MR成像表现程度无显著相关性。
PURPOSE: To determine whether knee pain, stiffness, and limited function in patients with different stages of osteoarthritis correlate with the degree of disease assessed on magnetic resonance (MR) images and radiographs.MATERIALS AND METHODS: Radiographs in 50 patients with varying degrees of osteoarthritis of the knee were assessed by using the the Western Ontario and McMaster University (WOMAC) osteoarthritis index and the Keligren-Lawrence (KL) scale. MR images were obtained and analyzed by two readers for cartilage lesions, bone marrow edema pattern, and ligamentous and meniscal lesions.RESULTS: Thirteen of 16 knees with a KL score of 4 showed full-thickness cartilage lesions and bone marrow edema pattern. Cruciate ligament tears were found in five of 12 knees with a KL score of 3 and in nine of 16 knees with a KL score of 4. While the KL score correlated significantly (P < .05) with the grade of cartilage lesions and, a substantially higher percentage of lesions with higher KL scores were found on MR images, the correlations between MR imaging findings and KL score versus clinical findings were not significant (P > .05). Significant differences between WOMAC scores were found only for the grades of cartilage lesions (P < .05).CONCLUSION: Cartilage lesions, bone marrow edema pattern, and meniscal and ligamentous lesions were frequently demonstrated on MR images in patients with advanced osteoarthritis. Clinical findings showed no significant correlations with KL score and extent of findings at MR imaging.