Conduct disorder and callous-unemotional traits in youth.
Conduct disorder and callous-unemotional traits in youth.
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DOI：
10.1056/nejmra1315612
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发表时间：
2014-12-04
期刊：
影响因子：
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通讯作者：
Pine DS
中科院分区：
文献类型：
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作者：
Blair RJ;Leibenluft E;Pine DS
“行为问题”一词指的是一种重复的违规行为，侵略性和无视他人的模式。最近，由于青年犯下的暴力事件以及《精神疾病诊断和统计手册》对行为障碍标准的修改，这些问题受到了越来越多的关注，行为障碍是一种涉及儿童和青少年经常性行为问题的综合症。青少年行为问题预示着药物滥用，犯罪行为和教育中断的风险增加;他们也会因人际痛苦和经济成本而产生相当大的社会负担。这篇评论总结了目前关于青年行为问题的数据，并强调了有希望的研究途径。以前的综述总结了关于结局、治疗和家族聚集的临床文献或关于机制和病理生理学的神经认知文献。目前的审查不同，更紧密地结合临床和神经认知的角度。
The term “conduct problems” refers to a pattern of repetitive rule-breaking behavior, aggression, and disregard for others. Such problems have received increased attention recently, owing to violent events perpetrated by youth and modifications in the Diagnostic and Statistical Manual of Mental Disorders (DSM) criteria for conduct disorder, a syndrome involving recurrent conduct problems in children and adolescents. Youth conduct problems are predictive of an increased risk of substance abuse, criminal behavior, and educational disruption; they also incur a considerable societal burden from interpersonal suffering and financial costs. This review summarizes current data on youth conduct problems and highlights promising avenues for research. Prior reviews have summarized either the clinical literature on outcome, treatment, and familial aggregation or the neurocognitive literature on mechanisms and pathophysiology. The current review differs by more tightly integrating clinical and neurocognitive perspectives.