Severe disturbance of higher cognition after bilateral frontal lobe ablation
Severe disturbance of higher cognition after bilateral frontal lobe ablation
复制标题
双侧额叶消融术后高级认知功能严重障碍
作者：
P. Eslinger;A. Damasio
在双侧眼眶和额叶内侧下部皮质消融后，患者的行为发生了深刻的变化，并保持了8年的稳定。虽然他不能履行个人和职业责任，但他的“可测量的”智商出类拔萃，因此被认为是一个“伪装者”。神经学和神经心理学检查在其他方面都完好无损。CT、MRI和SPET显示眼眶和额叶下部内侧皮质有局限性损害。所有其他脑区的结构和放射性模式都正常。这种动机障碍和复杂的社会行为在额叶上内侧或背外侧损害的对照病例中未见。
After bilateral ablation of orbital and lower mesial frontal cortices, a patient had profound changes of behavior that have remained stable for 8 years. Although he could not meet personal and professional responsibilities, his “measurable” intelligence was superior, and he was therefore considered a “malingerer.” Neurologic and neuropsychological examinations were otherwise intact. CT, MRI, and SPET revealed a localized lesion of the orbital and lower mesial frontal cortices. All other cerebral areas had normal structure and radioactivity patterns. Such impairments of motivation and complex social behavior were not seen in control cases with superior mesial or dorsolateral frontal lesions.