Prediction value of anti-Mullerian hormone (AMH) serum levels and antral follicle count (AFC) in hormonal contraceptive (HC) users and non-HC users undergoing IVF-PGD treatment

Prediction value of anti-Mullerian hormone (AMH) serum levels and antral follicle count (AFC) in hormonal contraceptive (HC) users and non-HC users undergoing IVF-PGD treatment
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DOI:
10.1080/09513590.2017.1320376
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发表时间:
2017-01-01
影响因子:
2
通讯作者:
Eldar-Geva, Talia
Eldar-Geva, Talia
中科院分区:
医学4区
文献类型:
--
作者:
Bas-Lando, Maayan;Rabinowitz, Ron;Eldar-Geva, Talia

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使用激素避孕药(HC)是非常流行的生育年龄,因此,卵巢储备的评估将是一个有用的工具,以准确地评估生殖潜力HC用户。我们进行了一项回顾性队列研究,41名HC使用者与57名接受IVF植入前遗传学诊断(PGD)的非HC使用者进行了比较,旨在评估HC对抗苗勒管激素(AMH)水平,小(2- 5 mm),大(6- 10 mm)和总窦卵泡计数(AFC)的影响以及这些标志物预测IVF结局的能力。大AFC(p=0.04)和卵巢体积(p
Use of hormone contraceptives (HC) is very popular in the reproductive age and, therefore, evaluation of ovarian reserve would be a useful tool to accurately evaluate the reproductive potential in HC users. We conducted a retrospective cohort study of 41 HC users compared to 57 non-HC users undergoing IVF-preimplantation genetic diagnosis (PGD) aiming to evaluate the effect of HC on the levels of anti-Mullerian hormone (AMH), small (2-5mm), large (6-10mm) and total antral follicle count (AFC) and the ability of these markers to predict IVF outcome. Significant differences in large AFC (p=0.04) and ovarian volume (p