Psychiatric illness and contraction abnormalities of the esophagus.
Psychiatric illness and contraction abnormalities of the esophagus.
复制标题
精神疾病和食道收缩异常。
DOI：
10.1056/nejm198312013092201
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发表时间：
1983
期刊：
影响因子：
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通讯作者：
P. Lustman
中科院分区：
文献类型：
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作者：
R. Clouse;P. Lustman
在六个月的时间内，50名患者转诊进行临床食管测压独立评估精神病诊断，以确定是否有任何精神疾病和食管动力障碍之间的关联。测压研究根据食管体的结果进行盲法分类。25例患者被归类为具有以下一种或多种收缩异常：平均波幅增加、平均波持续时间增加、异常运动反应频率增加或存在三峰波。25例患者中有21例（84%）被诊断为精神病，但13例血压正常的患者中只有4例（31%）被诊断为精神病（P <0.005），12例其他血压异常的患者中只有4例（33%）被诊断为精神病（P <0.01）。精神疾病与一组特定的食道收缩异常相关的事实可能为进一步研究情绪障碍与胃肠道运动障碍之间的关系提供了基础。
Over a six-month period 50 patients referred for clinical esophageal manometry were independently evaluated for psychiatric diagnoses to determine whether there was any association between psychiatric illness and esophageal motility disorders. The manometric studies were blindly classified according to findings in the esophageal body. Twenty-five patients were classified as having one or more of the following contraction abnormalities: an increase in mean wave amplitude, an increase in mean wave duration, an increased frequency of abnormal motor responses, or the presence of triple-peaked waves. Psychiatric diagnoses were made in 21 (84 per cent) of the 25 patients but in only 4 (31 per cent) of the 13 patients with normal manometric patterns (P less than 0.005) and 4 (33 per cent) of the 12 with other manometric abnormalities (P less than 0.01). The fact that psychiatric illness is associated with a specific cluster of esophageal contraction abnormalities may provide a basis for further investigation of the relation between emotional disturbances and disorders of gastrointestinal motility.
影响因子：
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作者：
L. Robins;J. Helzer;J. Croughan;K. Ratcliff
通讯作者：
L. Robins;J. Helzer;J. Croughan;K. Ratcliff