Effects of endocytosis on receptor-mediated signaling.
Effects of endocytosis on receptor-mediated signaling.
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DOI：
10.1016/j.ceb.2015.05.005
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发表时间：
2015-08
影响因子：
7.5
通讯作者：
von Zastrow M
中科院分区：
文献类型：
--
作者：
Irannejad R;Tsvetanova NG;Lobingier BT;von Zastrow M
细胞膜运输和信号转导的机制是紧密相连的。本综述讨论了如何在胞吞途径的膜贩运影响受体介导的信号。最近取得的进展的例子突出，集中在哺乳动物的内吞信号的联系。
Cellular mechanisms of membrane traffic and signal transduction are deeply interconnected. The present review discusses how membrane trafficking in the endocytic pathway impacts receptor-mediated signaling. Examples of recent progress are highlighted, focusing on the endocytosis-signaling nexus in mammals.