Failure of Indomethacin and Radiation to Prevent Blast-induced Heterotopic Ossification in a Sprague-Dawley Rat Model.
Failure of Indomethacin and Radiation to Prevent Blast-induced Heterotopic Ossification in a Sprague-Dawley Rat Model.
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吲哚美辛和辐射未能防止 Sprague-Dawley 大鼠模型中爆炸诱导的异位骨化。
DOI：
10.1097/corr.0000000000000594
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发表时间：
2019
影响因子：
4.2
通讯作者：
Pellegrini,VincentD
中科院分区：
文献类型：
--
作者：
Robertson,AstorD;Chiaramonti,AlexanderM;Nguyen,ThaoP;Jaffe,DavidE;Holmes,RobertE;Hanna,ELex;Rhee,JuongG;Barfield,WilliamR;Fourney,WilliamB;Stains,JosephP;Pellegrini,VincentD
背景尽管使用非甾体类药物和低剂量放射治疗已被证明在预防THA和髋臼骨折手术治疗后异位骨化（HO）方面有效，但这些方法在创伤性爆炸性截肢后尚未进行评估，其中HO是残肢中常见的并发症。
BackgroundAlthough use of nonsteroidal antiinflammatory drugs and low-dose irradiation has demonstrated efficacy in preventing heterotopic ossification (HO) after THA and surgical treatment of acetabular fractures, these modalities have not been assessed after traumatic blast amputations where HO is a common complication that can arise in the residual limb.