An elegant synthesis of Zetaclausenamide

An elegant synthesis of Zetaclausenamide
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DOI:
10.1016/j.ejmech.2007.05.010
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发表时间:
2008-04-01
影响因子:
6.7
通讯作者:
Huang, Liang
Huang, Liang
中科院分区:
医学1区
文献类型:
--
作者:
Ma, Nianchun;Wu, Kemei;Huang, Liang

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首次从药用植物Clausena lansium的叶片中分离得到保肝剂Zetaclausenamide,经Darzen缩合、光异构、最后环化六个步骤合成。(c) 2007年Elsevier Masson SAS。版权所有。
Zetaclausenamide, which was isolated as a hepatoprotective agent from the leaves of medicinal plant Clausena lansium, was synthesized for the first time in six steps including Darzen's condensation, photoisomerization, and the final cyclization reactions. (c) 2007 Elsevier Masson SAS. All rights reserved.