Level of renal function at the initiation of dialysis in the US end-stage renal disease population

Level of renal function at the initiation of dialysis in the US end-stage renal disease population
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DOI:
10.1046/j.1523-1755.1999.00779.x
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发表时间:
1999-12-01
影响因子:
19.6
通讯作者:
Levey, AS
Levey, AS
中科院分区:
医学1区
文献类型:
--
作者:
Obrador, GT;Arora, P;Levey, AS

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Background. More than 285,000 individuals in the United States suffer from end-stage renal disease (ESRD) and are treated predominantly by dialysis. Despite the high cost and poor outcomes of dialysis treatment for ESRD, there are few data about the level of renal function at the onset of ESRD and no established medical criteria for the initiation of dialysis.Methods. We report the level of serum creatinine and glomerular filtration rate (GFR) in 90,897 patients who began dialysis in the U.S. between April 1995 through September 1997. Data were obtained from the U.S. Renal Data System. GFR was predicted by an equation developed from the Modification of Diet in Renal Disease Study.Results. The mean (SD) serum creatinine was 8.5 (3.8) mg/dl. The mean (SD) predicted GFR was 7.1 (3.1) ml/min/1.73 m(2), with a range from 1 to 42 ml/min/1.73 m(2). The proportion of patients with predicted GFR of >10, 5 to 10, and