Functional and morphological studies of photodamaged skin on the hands of middle-aged Japanese golfers.
Functional and morphological studies of photodamaged skin on the hands of middle-aged Japanese golfers.
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日本中年高尔夫球手手部光损伤皮肤的功能和形态学研究。
DOI：
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发表时间：
2000
期刊：
影响因子：
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通讯作者：
H. Tagami
中科院分区：
文献类型：
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作者：
K. Kikuchi‐Numagami;T. Suetake;M. Yanai;M. Takahashi;M. Tanaka;H. Tagami
高尔夫球手手部的皮肤提供了一个合适的模型来研究长期阳光照射的影响，因为他们的一只手暴露在外部环境中，特别是阳光下，而另一只手在比赛中总是受到手套的保护。我们的目的是找出光损伤的影响，对中年日本人的皮肤表面的性质，通过使用非侵入性的方法。测定了皮肤的水合状态、角质层的水屏障功能和手背皮肤的颜色。在一项单独的研究中，我们通过使用从皮肤上取下的略微拉伸或放松位置的复制品来评估皮肤表面轮廓。我们发现一个显着的减少，暴露的皮肤的皮肤表面的水合作用相比，保护皮肤，而没有这样的差异被发现与经皮水分流失，一个参数的水屏障功能的SC。亮度的皮肤颜色也减少了在阳光下暴露的皮肤。结果显示，在放松位置上形成的大皱纹在暴露的皮肤上比在受保护的皮肤上更突出，而在轻微拉伸位置上观察到的细沟在前者上比后者浅。结果表明，长期暴露于外界环境，尤其是阳光下，高尔夫球手手部皮肤会发生形态和功能的变化。此外，发现生物工程非侵入性方法可用于以更定量的方式检测皮肤的早期光损伤，这在临床上是相当困难的。
The skin of golfers' hands provides a suitable model to study the effect of chronic sun exposure, because one of their hands is exposed to the outer environment, especially sunlight, while the other one is always protected by a glove during play. Our purpose was to find out the influence of photodamage on the properties of the skin surface of middle-aged Japanese by using non-invasive methods. We measured hydration state, and water barrier function of the stratum corneum (SC) and the color of the skin of the dorsum of the hands. In a separate study, we evaluated the skin surface contour by using replicas taken from the skin in a slightly stretched or relaxed position. We found a significant decrease in hydration of the skin surface of the exposed skin as compared to that of the protected skin, whereas no such difference was found with transepidermal water loss, a parameter for water barrier function of the SC. Luminance of skin color was also reduced in the sun-exposed skin. Replica analysis revealed that large wrinkles developing in a relaxed position were more prominent on the exposed than on the protected skin, while fine furrows noted in a slightly stretched position were shallower on the former than the latter. The data obtained indicate that the chronically exposed skin of golfers' hands shows morphological and functional changes resulting from long time exposure to the outer environment especially sunlight. Furthermore, bioengineering non-invasive methods are found to be useful to detect early photodamage of the skin in a more quantitative fashion which is rather difficult to demonstrate clinically.