Subjective and objective quality of life, levels of life skills, and their clinical determinants in outpatients with schizophrenia

Subjective and objective quality of life, levels of life skills, and their clinical determinants in outpatients with schizophrenia
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DOI:
10.1016/j.psychres.2006.05.017
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发表时间:
2008-02-28
影响因子:
11.3
通讯作者:
Ohmori, Tetsuro
Ohmori, Tetsuro
中科院分区:
医学2区
文献类型:
--
作者:
Aki, Hirofumi;Tornotake, Masahito;Ohmori, Tetsuro

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本研究旨在探讨精神分裂症门诊患者主客观生活质量(QOL)、生活技能水平及其临床决定因素之间的关系。对64例门诊患者的数据进行分析。主观生活质量采用精神分裂症生活质量量表(SQLS),客观生活质量采用生活质量量表(QLS)。患者家属完成了生活技能简介(LSP)。临床症状也用精神分裂症简短评定量表(BPRS)和卡尔加里抑郁量表(CDSS)进行评估。只有动机/能量量表与生活质量相关,而其他量表与生活质量相关。家庭评定的LSP与SQLS和QLS均呈显著相关。CDSS评分预测SQLS各量表,BPRS阴性症状评分预测QLS。LSP由BPRS阴性症状评分和CDSS评分独立预测。这些结果表明,患者的生活质量可以通过家庭成员测量的生活技能来预测,并建议积极治疗抑郁和阴性症状,以提高患者的生活质量和生活技能。2006爱思唯尔爱尔兰有限公司版权所有。
The purpose of the present Study is to investigate the relationships among subjective and objective quality of life (QOL), and levels of life skills, and their clinical determinants in outpatients with schizophrenia by using schizophrenia disease-specific QOL measures.. Data collected from 64 Outpatients were analyzed. Subjective QOL was measured with the Schizophrenia Quality of Life Scale (SQLS) and objective QOL with the Quality of Lire Scale (QLS). Patients' family members completed the Life Skills Profile (LSP). Clinical symptoms were also assessed with several scales including the Brief Psychiatric Rating Scale (BPRS) and the Calgary Depression Scale for Schizophrenia (CDSS). Only the motivation/energy scale, but lot the Other scales of the SQLS, correlated with the QLS. The LSP rated by the family showed significant correlations with both the SQLS and the QLS. The CDSS score predicted each scale of the SQLS, and the BPRS negative symptoms score predicted the QLS. The LSP was predicted by the BPRS negative symptoms score and the CDSS score independently. These results indicate that the Patient's QOL could be predicted by the life: skills measured by a family member and Suggest that active treatment for depressive and negative symptoms might be recommended to improve the patient's QOL and life skills. (c) 2006 Elsevier Ireland Ltd. All rights reserved.