New Intrauterine Growth Curves Based on United States Data
New Intrauterine Growth Curves Based on United States Data
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DOI：
10.1542/peds.2009-0913
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发表时间：
2010-02-01
期刊：
影响因子：
8
通讯作者：
Zemel, Babette S.
中科院分区：
文献类型：
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作者：
Olsen, Irene E.;Groveman, Sue A.;Zemel, Babette S.
目的：本研究的目的是创建和验证新的宫内体重、长度和头围生长曲线，使用当代、大的、种族多样化的美国样本，并与Lubchenco曲线进行比较。方法：使用美国33个州248家医院（1998 - 2006年）391 681名出生时22至42周的婴儿（儿科医疗组）的出生体重、身长、头围、估计胎龄、性别和种族的数据。单独的子样本用于创建和验证曲线。采用Lambda Mu Sigma （LMS）方法绘制平滑的百分位曲线（第3 ~ 97位）。用验证样本验证曲线的代表性。将新曲线与Lubchenco曲线进行了比较。结果：最终样本包括257 855名存活至出院的单胎婴儿（57.2%为男性）。创建了性别特异性的体重、长度和头围随年龄变化的曲线（n = 130 111），并成功验证了这一曲线（n = 127 744）。使用Lubchenco曲线的小胎龄和大胎龄分类与每个胎龄的新曲线有显著差异(P
OBJECTIVE: The objective of this study was to create and validate new intrauterine weight, length, and head circumference growth curves using a contemporary, large, racially diverse US sample and compare with the Lubchenco curves.METHODS: Data on 391 681 infants (Pediatrix Medical Group) aged 22 to 42 weeks at birth from 248 hospitals within 33 US states (19982006) for birth weight, length, head circumference, estimated gestational age, gender, and race were used. Separate subsamples were used to create and validate curves. Smoothed percentile curves (3rd to 97th) were created by the Lambda Mu Sigma (LMS) method. The validation sample was used to confirm representativeness of the curves. The new curves were compared with the Lubchenco curves.RESULTS: Final sample included 257 855 singleton infants (57.2% male) who survived to discharge. Gender-specific weight-, length-, and head circumference-for-age curves were created (n = 130 111) and successfully validated (n = 127 744). Small-for-gestational age and large-for-gestational age classifications using the Lubchenco curves differed significantly from the new curves for each gestational age (all P