Body iron stores and early neurologic deterioration in acute cerebral infarction
Body iron stores and early neurologic deterioration in acute cerebral infarction
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DOI：
10.1212/wnl.54.8.1568
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发表时间：
2000-04-25
期刊：
影响因子：
9.9
通讯作者：
Rama, R
中科院分区：
文献类型：
--
作者：
Dávalos, A;Castillo, J;Rama, R
背景：铁依赖性自由基的形成与脑缺血时更大的损伤有关。作者分析了急性缺血性卒中患者体内铁储备增加是否与早期神经功能恶化和兴奋性氨基酸释放相关。研究方法：对100例脑梗死患者入院时血浆和脑脊液中的铁蛋白、总铁和谷氨酸浓度进行了测定，
Background: Iron-dependent free radicals formation has been related to greater damage in cerebral ischemia. The authors analyzed whether increased body iron stores were associated with early neurologic worsening and excitatory amino acid release in patients with acute ischemic stroke. Methods: Ferritin, total iron, and glutamate concentrations in plasma and CSF were measured on admission in 100 consecutive patients with a cerebral infarction of