Prevention of Borrelia burgdorferi transmission in guinea pigs by tick immunity
Prevention of Borrelia burgdorferi transmission in guinea pigs by tick immunity
复制标题
DOI：
10.4269/ajtmh.1998.58.780
复制
发表时间：
1998-06-01
影响因子：
3.3
通讯作者：
Kantor, FS
中科院分区：
文献类型：
--
作者：
Nazario, S;Das, S;Kantor, FS
We examined the effect of repeated infestation of guinea pigs with Ixodes scapularis on the capacity of ticks to transmit Borrelia burgdorferi infection. Repeated challenges with nymphs or larvae lead to a reduction in duration of nymphal tick attachment and weight of recovered ticks consistent with the development of tick immunity. Only one of 18 I. scapularis-immune guinea pigs challenged with B. burgdorferi-infected nymphal ticks became infected, whereas 10 of 18 naive guinea pigs similarly challenged became infected. We conclude that tick immunity interferes with borrelial transmission.
