High prevalence of hantavirus infection in Indian communities of the Paraguayan and Argentinean Gran Chaco
High prevalence of hantavirus infection in Indian communities of the Paraguayan and Argentinean Gran Chaco
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DOI：
10.4269/ajtmh.1998.59.438
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发表时间：
1998-09-01
影响因子：
3.3
通讯作者：
Hjelle, B
中科院分区：
文献类型：
--
作者：
Ferrer, JF;Jonsson, CB;Hjelle, B
居住在巴拉圭西部的193名印第安人中有78人（40.4%）和居住在阿根廷北部萨尔塔省的222名印第安人中有38人（17.1%）有血清学证据表明过去感染过Sin nom布雷样汉坦病毒。在这两个人群中，血清患病率都随着年龄的增长而增加，巴拉圭人在18岁时和萨尔塔人在35岁时的增幅最为显著。两种人群的最高患病率分别为66.6%和44.0%，出现在10 - 53岁的印第安人。虽然在巴拉圭印第安人中没有观察到性别差异，但在萨尔塔人群中，男性的血清患病率高于女性。观察到熟悉的感染聚集性。数据表明，大查科的印第安人经常接触到一种类似辛诺布雷的病毒，并在感染后存活下来。讨论了这种新型流行病学的可能解释。
Serologic evidence of past infection with a Sin Nombre-like hantavirus(es) was demonstrated in 78 (40.4%) of 193 Indians living in western Paraguay and in 38 (17.1%) of 222 Indians inhabiting the Salta province of northern Argentina. In both populations seroprevalence increased with age, with the most striking increase occurring at 18 years of age in the Paraguayan population and at 35 years of age in the Salta population, The peak prevalences in both populations (66.6% and 44.0%, respectively) were seen in Indians > 53 years old. Although no sex difference was observed in the Paraguayan Indians, in the Salta population seroprevalence was greater in males than in females. Familiar clustering of the infection was observed. The data indicate that the Indian populations of the Gran Chaco are frequently exposed to and survive infection with a Sin Nombre-like virus(es). Possible explanations of this novel epidemiology are discussed.