Impact of Racial/Ethnic Discrimination on Quality of Life Among Breast Cancer Survivors.
Impact of Racial/Ethnic Discrimination on Quality of Life Among Breast Cancer Survivors.
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种族/民族歧视对乳腺癌幸存者生活质量的影响。
DOI：
10.1093/aje/kwac208
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发表时间：
2023
影响因子：
5
通讯作者：
Gomez,ScarlettLin
中科院分区：
文献类型：
--
作者：
Shariff-Marco,Salma;Sangaramoorthy,Meera;Ellis,Libby;Thomsen,Catherine;Roh,JaniseM;Kroenke,Candyce;Valice,Emily;Kwan,MarilynL;Ambrosone,Christine;Kushi,Lawrence;Gomez,ScarlettLin
虽然在获得保健、治疗和癌症结果方面的种族/民族差异有充分的记录，但种族/民族歧视对癌症幸存者的影响尚不清楚。我们使用线性回归模型，研究了2006-2013年间从Kaiser Permanente北加州综合医疗保健系统的Pathways研究中招募的3991名乳腺癌女性患者的生活质量（QoL）与自我报告的歧视之间的关系。总体而言，31%的女性报告遭受种族/民族歧视，种族/民族差异（非西班牙裔黑人女性为82%，非西班牙裔白人女性为19%）和出生（外国出生的西班牙裔女性为40%，美国出生的亚裔美国女性为76%）。在完全调整的模型中，经历种族/民族歧视与较低的生活质量相关。没有报告歧视的女性的平均生活质量评分为119.6(95%可信区间（CI）： 102.0, 137.1)，报告一些歧视/小于中位数水平的女性的平均生活质量评分为115.5 (95% CI: 98.0, 133.0)，报告更多歧视/大于或等于中位数水平的女性的平均生活质量评分为110.2 （95% CI: 92.7, 127.7）。在使用被动应对策略或生活在社会经济地位高的社区、高度隔离的社区或非种族飞地的社区的妇女中，歧视与较低的生活质量有关。在乳腺癌幸存者中，生活质量评分的临床意义差异与种族/民族歧视有关。需要进一步的研究来了解这些社会因素影响生存结果的潜在途径。
Although racial/ethnic disparities in health-care access, treatment, and cancer outcomes are well documented, the impact of racial/ethnic discrimination on cancer survivorship is unclear. We examined associations between quality of life (QoL) and self-reported discrimination among 3,991 women with breast cancer recruited during 2006–2013 from the Pathways Study in the Kaiser Permanente Northern California integrated health-care system, using linear regression models. Overall, 31% of women reported experiencing racial/ethnic discrimination, with differences by race/ethnicity (82% among non-Hispanic Black women vs. 19% among non-Hispanic White women) and nativity (40% among foreign-born Hispanic women vs. 76% among US-born Asian-American women). Experiencing racial/ethnic discrimination was associated with lower QoL in fully adjusted models. The mean QoL score was 119.6 (95% confidence interval (CI): 102.0, 137.1) for women who did not report discrimination, 115.5 (95% CI: 98.0, 133.0) for those who reported some discrimination/less than the median level, and 110.2 (95% CI: 92.7, 127.7) for those who reported more discrimination/greater than or equal to the median level. Discrimination was associated with lower QoL among women who used passive coping strategies or lived in neighborhoods with high neighborhood socioeconomic status, neighborhoods with high levels of segregation, or non–ethnic enclaves. Among breast cancer survivors, clinically meaningful differences in QoL scores were associated with racial/ethnic discrimination. Additional studies are needed to understand potential pathways through which these social factors affect survivorship outcomes.
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DOI：
--
发表时间：
1987
期刊：
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影响因子：
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作者：
H. Shidnia;A. Hartsough;E. Weisberger;N. Hornback
通讯作者：
N. Hornback
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1988
期刊：
International Journal of Radiation Oncology, Biology, Physics
影响因子：
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影响因子：
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影响因子：
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发表时间：
1969
期刊：
The American journal of roentgenology, radium therapy, and nuclear medicine
影响因子：
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作者：
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