Non-enzymatic lactate detection by an extended-gate type organic field effect transistor
Non-enzymatic lactate detection by an extended-gate type organic field effect transistor
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DOI：
10.1088/1361-6641/abb288
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发表时间：
2020-11-01
影响因子：
1.9
通讯作者：
Minami, Tsuyoshi
中科院分区：
文献类型：
--
作者：
Didier, Pierre;Minami, Tsuyoshi
报道了一种基于扩展栅型有机场效应晶体管（OFET）的乳酸（LA）非酶化学传感器。该器件由人工受体苯硼酸衍生物修饰的扩展栅电极作为检测部分和OFET作为驱动部分组成。LA检测的机制依赖于OFET与LA动态共价键合后转移特性的变化。在评价器械检测LA的能力后，将其应用于选择性研究。该报告证明了使用基于OFET的传感器装置进行非酶LA检测的可能性。
A non-enzymatic chemical sensor for lactate (LA) detection based on an extended-gate type organic field-effect transistor (OFET) is reported. The proposed device is composed of an extended-gate electrode modified by an artificial receptor phenylboronic acid derivative as the detection part and the OFET as the drive part. The mechanism of LA detection relies on the changes in transfer characteristics of the OFET upon dynamic covalent bonding with LA. After evaluating the ability of the device to detect LA, it was applied to the selectivity study. This report proved the possibility of using the OFET-based sensor device for non-enzymatic LA detection.