Increased brain activity in frontal and parietal cortex underlies the development of visuospatial working memory capacity during childhood
Increased brain activity in frontal and parietal cortex underlies the development of visuospatial working memory capacity during childhood
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DOI：
10.1162/089892902317205276
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发表时间：
2002-01-01
影响因子：
3.2
通讯作者：
Westerberg, H
中科院分区：
文献类型：
--
作者：
Klingberg, T;Forssberg, H;Westerberg, H
这项研究的目的是确定大脑活动的变化与工作记忆(WM)容量的增加有关，这种变化发生在儿童和成年早期。功能磁共振成像(FMRI)被用来测量9到18岁的受试者在执行视觉空间WM任务和基线任务时的脑活动。在工作记忆任务的执行过程中，年龄较大的儿童在额叶上皮质和顶叶内皮质的激活程度高于年龄较小的儿童。第二项分析发现，工作记忆能力与相同区域的大脑活动显著相关。众所周知，这些额叶和顶叶区域参与了注意力和空间工作记忆的控制。这些区域的功能发展可能在儿童时期的认知发展中起重要作用。
The aim of this study was to identify changes in brain activity associated with the increase in working memory (WM) capacity that occurs during childhood and early adulthood. Functional MRI (fMRI) was used to measure brain activity in subjects between 9 and 18 years of age while they performed a visuospatial WM task and a baseline task. During performance of the WM task, the older children showed higher activation of cortex in the superior frontal and intraparietal cortex than the younger children did. A second analysis found that WM capacity was significantly correlated with brain activity in the same regions. These frontal and parietal areas are known to be involved in the control of attention and spatial WM. The development of the functionality in these areas may play an important role in cognitive development during childhood.