PULMONARY-FUNCTION OF UNITED-STATES COAL-MINERS RELATED TO DUST EXPOSURE ESTIMATES
PULMONARY-FUNCTION OF UNITED-STATES COAL-MINERS RELATED TO DUST EXPOSURE ESTIMATES
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DOI：
10.1164/ajrccm/145.3.605
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发表时间：
1992-03-01
期刊：
影响因子：
--
通讯作者：
HODOUS, TK
中科院分区：
文献类型：
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作者：
ATTFIELD, MD;HODOUS, TK
这项对7139名美国矿工进行的研究使用线性回归分析，将累积粉尘暴露估计值与1969至1971年间进行的体检期间测量的几个肺功能变量联系起来。暴露数据包括根据地下气载粉尘采样测量的大型数据库新得出的截至检查期间的累积粉尘暴露估计值。在累积暴露与FEV1、FVC和FEV1/FVC比率之间发现了负相关(p<；0.001)。总体而言，这些关系与报道的英国煤矿工人的关系相似。总体而言，结果表明，煤矿粉尘暴露对肺功能的不利影响，即使在没有放射学检测到的尘肺病的情况下也会发生。
This study of 7,139 U.S. coal miners used linear regression analysis to relate estimates of cumulative dust exposure to several pulmonary function variables measured during medical examinations undertaken between 1969 and 1971. The exposure data included newly derived cumulative dust exposure estimates for the period up to time of examination based on large data bases of underground airborne dust sampling measurements. Negative associations were found between measures of cumulative exposure and FEV1, FVC, and the FEV1/FVC ratio (p < 0.001). In general, the relationships were similar to those reported for British coal miners. Overall, the results demonstrate an adverse effect of coal mine dust exposure on pulmonary function that occurs even in the absence of radiographically detected pneumoconiosis.