Studying Hedgehog Signaling During Mouse Neural Tube Development.
Studying Hedgehog Signaling During Mouse Neural Tube Development.
复制标题
研究小鼠神经管发育过程中的 Hedgehog 信号传导。
DOI：
10.1007/978-1-0716-1701-4_6
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发表时间：
2022
期刊：
影响因子：
--
通讯作者：
Mukhopadhyay,Saikat
中科院分区：
文献类型：
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作者：
Constable,Sandii;White,Kevin;Somatilaka,BandarigodaNipunika;Mukhopadhyay,Saikat
神经管中腹侧神经祖细胞的身份在很大程度上依赖于Hedgehog（Hh）信号。染色模式的变化是异常Hh信号传导的极好指标。在这里，我们描述的基本协议，染色的祖先群体的基础上转录因子的表达。我们还提供了一个概述纤毛和中心体染色的神经管。
The identity of ventral neural progenitors in the neural tube is largely dependent on Hedgehog (Hh) signaling. Variations in staining patterns are excellent indicators of aberrant Hh signaling. Here we describe the basic protocol to stain for progenitor populations based on transcription factor expression. We also provide an overview of ciliary and centrosomal staining in the neural tube.