Diverticular disease of the large bowel in Singapore
Diverticular disease of the large bowel in Singapore
复制标题
新加坡的大肠憩室病
DOI：
10.1007/bf02554125
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发表时间：
1986
影响因子：
3.9
通讯作者：
Yoke‐Sun Lee
中科院分区：
文献类型：
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作者：
Yoke‐Sun Lee
在尸检时，14 岁以上的人连续切除了 114 条大肠，并检查是否患有憩室病。 194 名患者（19%）患有憩室病。这种病变出现在生命早期，也就是二十岁之后。 60 岁之前，男性比女性更容易受到影响。中国男性的憩室病明显多于马来亚男性（P<0.01）和印度男性（P<0.02）。中国男性的憩室病发病率也明显高于中国女性。右结肠受累为主，该疾病尤其影响升结肠和盲肠。在所有三个主要种族群体以及新加坡出生和外国出生的新加坡人中都观察到了这种模式。右侧憩室病的病因尚不清楚。看来，虽然采用西方饮食可能会影响憩室病的患病率，但好发部位更多地取决于种族或遗传倾向。所有憩室组织学检查均为假，其中包括 39 个（20%）孤立性憩室。孤立性憩室的分布与多发性憩室相似。有人认为，孤立性憩室病和多发性憩室病属于同一疾病谱系的一部分。
One thousand fourteen consecutive large intestines were removed at autopsy from persons over the age of 14 years and examined for diverticular disease. Diverticulosis was encountered in 194 patients (19 percent). The lesion appeared early in life, after the second decade. Men were affected more frequently than women before the age of 60 years. Chinese men had significantly more diverticular disease than Malayan men (P<0.01) and Indian men (P<0.02). Chinese men also had significantly more diverticular disease than Chinese women. There was a predominance of right colon involvement, with the disease affecting especially the ascending colon and cecum. This pattern was observed in all three major ethnic groups, and in both the Singapore-born and foreign-born Singaporeans. The cause of right-sided diverticulosis is unknown. It appears that, while adoption of the western diet may influence the prevalence of diverticular disease, the site of predilection is determined more by racial or genetic predisposition. All diverticular examined histologically were false, including 39 (20 percent) solitary diverticula. The distribution of solitary diverticula was similar to that of multiple diverticulosis. It is suggested that solitary and multiple diverticulosis are part of the spectrum of the same disease.