Lingual lymph nodes in patients with squamous cell carcinoma of the tongue and the floor of the mouth
Lingual lymph nodes in patients with squamous cell carcinoma of the tongue and the floor of the mouth
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DOI：
10.1002/hed.25340
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发表时间：
2018-11-01
影响因子：
2.9
通讯作者：
Zou, Hai-xiao
中科院分区：
文献类型：
--
作者：
Jia, Jun;Jia, Meng-qi;Zou, Hai-xiao
背景口腔鳞状细胞癌（SCC）治疗失败的主要原因是局部复发。我们研究了舌淋巴结（LLN）在舌和口底SCC复发中的作用。方法选取2012年至2017年期间接受治疗的111例舌和口底鳞状细胞癌患者作为研究对象。将病理检查证实有舌淋巴结转移的患者分为LNN组。比较无LLN组和LLN组之间的人口统计学和临床数据差异。结果LLN的总发生率为17.12%（19/111），其中5例（4.5%）出现LLN转移。所有LLN转移患者的颈部淋巴结状态均为N2分类。LLN的发生和转移与舌和口底SCC的病理类型有关。结论舌和口底鳞状细胞癌患者的LLN是罕见的，它们可以被省略。这些LLN的解剖将有利于那些病理学分级较高的患者。
Background The treatment failure for oral squamous cell carcinoma (SCC) frequently takes the form of local and regional recurrences. We investigated the role of lingual lymph nodes (LLNs) in the recurrence of SCC of the tongue and the floor of the mouth. Methods A total of 111 patients with SCC of the tongue and the floor of the mouth who received treatment between 2012 and 2017 were included in this study. The patients with lingual lymph nodes that were confirmed to be metastasis on pathological examination were classified into the LNN group. The demographic and clinical data differences between the No-LLN group and the LLN group were compared. Statistical analyses were performed using the Pearson chi-square test Results The total incidence of LLNs was 17.12% (19/111) and 5 patients (4.5%) demonstrated LLN metastases. All the patients with LLN metastases had a neck lymph node status of N2 classification. The incidence and metastasis of the LLNs were associated with pathological classifications of SCC of the tongue and the floor of the mouth. Conclusions LLNs are rare in patients with SCC of the tongue and the floor of the mouth, and they would be ready to be omitted. The dissection of these LLNs would be of benefit to those patients with advanced pathological grade.