THE CUSUM TEST OF HOMOGENEITY WITH AN APPLICATION IN SPONTANEOUS-ABORTION EPIDEMIOLOGY
THE CUSUM TEST OF HOMOGENEITY WITH AN APPLICATION IN SPONTANEOUS-ABORTION EPIDEMIOLOGY
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DOI：
10.1002/sim.4780040408
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发表时间：
1985-10-01
影响因子：
2
通讯作者：
KLINE, J
中科院分区：
文献类型：
--
作者：
LEVIN, B;KLINE, J
我们测试的假设同质性随着时间的推移，在一个事件的发生率与修改页的累积和（cusum）的程序。修改借鉴了无差异区的方法来测试，非常适合于回顾性数据的流行病学研究。我们提供的程序来评估的显着性水平的最大观察到的累积值发生在一个序列的固定长度。我们无条件地以已知的事件基线率进行推断，并有条件地以未知基线率的观察到的边缘进行推断。从纽约市一家医院收集的5年数据用于说明染色体正常、三体、X-单体和三倍体自然流产比例波动研究中的改良累积和检验。
We test the hypothesis of homogeneity over time in the rate of an event with a modification of Page's cumulative sum (cusum) procedure. The modification draws on an indifference zone approach to testing that is well suited to the epidemiologic study of retrospective data. We provide procedures for evaluating the significance level of the largest observed cusum value occurring in a sequence of fixed length. We draw inferences unconditionally with a known baseline rate of the event, and conditionally on observed margins with unknown baseline rate. Data collected over a five year period from one New York City hospital serve to illustrate the modified cusum test in a study of fluctuations in the proportions of chromosomally normal, trisomic, X‐monosomic and triploid spontaneous abortions.