Effect of pretreating porous webs on stromal fibroplasia in vivo.
Effect of pretreating porous webs on stromal fibroplasia in vivo.
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预处理多孔网对体内基质纤维增生的影响。
DOI：
10.1002/jbm.820280209
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发表时间：
1994
期刊：
影响因子：
--
通讯作者：
Franzblau,C
中科院分区：
文献类型：
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作者：
Trinkaus-Randall,V;Banwatt,R;Wu,XY;Leibowitz,HM;Franzblau,C
我们以前已经证明，角膜基质细胞在多孔网被插入板层间角膜袋后穿透并沉积胶原。在这些研究中，我们的目标是确定多孔盘的预处理是否持续42天。我们用来确定预处理是否影响伤口愈合的标准是：胶原沉积，纤维增生程度，椎间盘内角质形成细胞的合成率，以及是否有水肿。我们的结果表明，预植基质角质细胞提高了总的合成率，特别是增加了网状结构中沉积的胶原量。©1994 John Wiley&Sons，Inc.
We have previously demonstrated that keratocytes penetrate and deposit collagen after a porous web is inserted into interlamellar corneal pockets. In these studies our goal was to determine whether pretreatment of the porous discs were followedin vivofor a period of 42 days. The criteria we used to determine whether pretreatment affected wound healing were: collagen deposition, extent of fibroplasia, the synthetic rate of keratocytes within the disc, and lack of edema. Our results indicate that preseeding with stromal keratocytes enhanced the overall synthetic rate and specifically enhanced the amount of collage deposited within the web. © 1994 John Wiley & Sons, Inc.