Occupational lifting during pregnancy and risk of fetal death in a large national cohort study

Occupational lifting during pregnancy and risk of fetal death in a large national cohort study
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DOI:
10.5271/sjweh.3335
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发表时间:
2013-07-01
影响因子:
6.3
通讯作者:
Andersen, Anne-Marie Nybo
Andersen, Anne-Marie Nybo
中科院分区:
医学2区
文献类型:
--
作者:
Juhl, Mette;Strandberg-Larsen, Katrine;Andersen, Anne-Marie Nybo

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目的本研究的目的是检查之间的关联职业升降和胎儿死亡的风险根据gestational age.Methods我们使用的数据从丹麦国家出生队列(1996-2002年)。在71 500名从事职业活动的妇女中,有2 886名胎儿死亡。在妊娠第16周左右的访谈中收集了关于举重和相关协变量的信息。大多数胎儿丢失(N=2032)发生在计划的访谈之前,并从这些女性中回顾性收集暴露数据。我们分析了早期流产(= 22周),使用Cox回归模型与胎龄为基础的时间variable.Results调整后的早期流产风险增加的频率,每天升降机和总负荷解除每天。例如,与非举重者相比,每天总重量负荷为101-200 kg的危险比为1.38 [95%置信区间(95%CI)1.10-1.74],而每天总重量负荷>1000 kg的危险比为2.02(95%CI 1.23-3.33)(趋势P
Objective The aim of the present study was to examine the association between occupational lifting and the risk of fetal death according to gestational age.Methods We used data from the Danish National Birth Cohort (1996-2002). Among 71 500 occupationally active women, 2886 experienced a fetal death. Information on lifting and relevant covariates was collected in interviews around week 16 of pregnancy. The majority of fetal losses (N=2032) happened before the scheduled interview, and exposure data were collected retrospectively from these women. We analyzed early miscarriage (= 22 weeks), using Cox-regression models with gestational age as the underlying time variable.Results The adjusted early miscarriage risk increased with frequency of daily lifts and total burden lifted per day. For example, the hazard ratio was 1.38 [95% confidence interval (95% CI) 1.10-1.74] for a total weight load per day of 101-200 kg and 2.02 (95% CI 1.23-3.33) for a daily load >1000 kg as compared to non-lifters (P for trend