Prevalence of seafood allergy in the United States determined by a random telephone survey
Prevalence of seafood allergy in the United States determined by a random telephone survey
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DOI：
10.1016/j.jaci.2004.04.018
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发表时间：
2004-07-01
影响因子：
14.2
通讯作者：
Sampson, HA
中科院分区：
文献类型：
--
作者：
Sicherer, SH;Muñoz-Furlong, A;Sampson, HA
背景资料：海鲜过敏是潜在的严重，但这组食物过敏在美国人口的患病率尚未determined.Objective：估计海鲜（鱼，贝类）过敏的患病率在美国。方法：我们进行了一项全国性的，横断面，随机电话调查，通过使用标准化的问卷。标准预先建立，以确定海鲜过敏的报告令人信服的症状和医生evaluation.Results：共有5529户完成了调查（67.3%的参与率），代表人口普查的14,948人。5.9%（95%CI，5.3%-6.6%）的家庭和个人报告了根据既定标准定义的鱼类或贝类过敏，具体如下：任何海鲜过敏2.3%（95%CI，2%-2.5%），贝类2%，鱼类0.4%，两种类型均为0.2%。海鲜过敏在成人中比儿童更常见（2.8%比0.6%; P < .001），女性比男性更常见（3.6%比2%; P < .001）。58%报告了复发反应，超过50%报告了呼吸困难或咽喉发紧，16%使用肾上腺素治疗。尽管如此，只有8.6%的患者接受了自我注射肾上腺素。在对任何鱼类过敏的人中，对多种鱼类有反应的比例为67%;甲壳类动物的反应率为38%，软体动物的反应率为49%;只有14%的甲壳类动物过敏者报告软体动物过敏。结论：2.3%的总人口（约660万美国人）报告了医生诊断和/或令人信服的海鲜过敏。受影响的个人通常报告经常性，有时严重的反应，表明海鲜过敏是一个重大的健康问题。
Background: Seafood allergy is potentially severe, but the prevalence of this group of food allergies in the US population has not been determined.Objective: To estimate the prevalence of seafood (fish, shellfish) allergy in the United States.Methods: We performed a nationwide, cross-sectional, random telephone survey by using a standardized questionnaire. Criteria were established in advance to define seafood allergy by report of convincing symptoms and physician evaluation.Results: A total of 5529 households completed the survey (67.3% participation rate), representing a census of 14,948 individuals. Fish or shellfish allergy defined by established criteria was reported in 5.9% (95% CI, 5.3%-6.6%) of households and among individuals as follows: 2.3% (95% CI, 2%-2.5%) for any seafood allergy, 2% for shellfish, 0.4% for fish, and 0.2% for both types. Seafood allergy was more common in adults compared with children (2.8% vs 0.6%; P < .001) and in women compared with men (3.6% vs 2%; P < .001). Recurrent reactions were reported by 58%, dyspnea or throat tightness was reported by more than 50%, and 16% were treated with epinephrine. Despite this level of acuity, only 8.6% were prescribed self-injectable epinephrine. The rate of reactions to multiple fish among those with any fish allergy was 67%; for Crustacea the rate was 38%, and for mollusks the rate was 49%; only 14% with crustacean allergy reported a mollusk allergy.Conclusions: Physician-diagnosed and/or convincing seafood allergy is reported by 2.3% of the general population, or approximately 6.6 million Americans. Affected individuals typically report recurrent and sometimes severe reactions, indicating that seafood allergy represents a significant health concern.