Treatment of ocular disease in eczema herpeticum.
Treatment of ocular disease in eczema herpeticum.
复制标题
治疗疱疹性湿疹的眼部疾病。
DOI：
10.1016/s0002-9394(14)76344-5
复制
发表时间：
1990
影响因子：
4.2
通讯作者：
Ostler,HB
中科院分区：
文献类型：
--
作者：
Margolis,TP;Ostler,HB
Individuals with atopic dermatitis are particularly susceptible to herpes simplex viral infection and may develop dissemination (eczema herpeticum). Additionally, they may develop severe and bilateral herpetic ocular disease. The keratitis is commonly complicated by stromal scarring and slow epithelial healing despite topical antiviral therapy. We treated three patients who had herpetic keratoconjunctivitis associated with eczema herpeticum. In all three cases the keratitis resolved promptly (48 to 72 hours) without residual scarring after treatment with systemic acyclovir and topical trifluridine. The combined use of systemic acyclovir and topical trifluridine may be of similar value in treating all cases of atopic herpetic keratitis.
