Analysis of the third and fourth cell cycles of mouse early development.

Analysis of the third and fourth cell cycles of mouse early development.
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小鼠早期发育的第三和第四细胞周期的分析。

DOI:
10.1530/jrf.0.0760393
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发表时间:
1986
期刊:
Journal of reproduction and fertility
影响因子:
--
通讯作者:
M. Johnson
M. Johnson
中科院分区:
--
文献类型:
--
作者:
R. Smith;M. Johnson

文献摘要

被引文献

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在与先前的卵裂分裂同步的卵裂球群体中,分析了早期小鼠发育的第三个(4细胞)和第四个(8细胞)细胞周期。用微密度法测定DNA含量。卵裂球进入这些细胞周期在单个胚胎内和胚胎之间显示出相当大的异质性。这种异质性在第四个细胞周期比在第三个细胞周期更大。第三个细胞周期的组成期分别为G1 = 1 h, S = 7 h, G2 + M = 2-5 h,第四个细胞周期的组成期分别为G1 = 2 h, S = 7 h, G2 + M = 1-3 h。
The third (4-cell) and fourth (8-cell) cell cycles of early mouse development have been analysed in populations of blastomeres synchronized to the preceding cleavage division. DNA content was measured microdensitometrically. The entry of blastomeres into these cell cycles showed considerable heterogeneity both within and between individual embryos. This heterogeneity was greater in the fourth than in the third cell cycle. The component phases of the third cell cycle were estimated as G1 = 1 h, S = 7 h, and G2 + M = 2-5 h, and those of the fourth cell cycle as G1 = 2 h, S = 7 h, and G2 + M = 1-3 h.