DIHYDROXYACETONE TEST AS A SUBSTITUTE FOR THE DANSYL CHLORIDE TEST

DIHYDROXYACETONE TEST AS A SUBSTITUTE FOR THE DANSYL CHLORIDE TEST
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DOI:
10.1159/000247324
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发表时间:
1993-01-01
期刊:
影响因子:
3.4
通讯作者:
PIERARDFRANCHIMONT, C
PIERARDFRANCHIMONT, C
中科院分区:
医学3区
文献类型:
--
作者:
PIERARD, GE;PIERARDFRANCHIMONT, C

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丹磺酰氯试验的危害不可忽略。我们引入二羟丙酮试验作为安全的替代品。突出了几个优点,包括通过L*a*B*(亮度)中的色度学容易且可重复地测量皮肤颜色的改变。色调。色度)模式。在D-Squame(R)角质层收集物上,“体内”和“体外”揭示了随着时间的颜色变化以及由某些清洁护肤产品引起的DHA诱导的色素沉着的消退。
The hazards of the dansyl chloride test are not negligible. We introduce the dihydroxyacetone test as a safe substitute. Several advantages are highlighted including easy and reproducible measurements of the modifications in skin color by chromometry in the L*a*b* (luminance. hue. chroma) mode. The color variations in time as well as the fade-out of DHA-induced pigmentation by some cleansing skin care products are revealed 'in vivo' as 'ex vivo' on D-Squame(R) collections of stratum corneum.