Severe community-acquired pneumonia

Severe community-acquired pneumonia
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DOI:
10.1016/s0749-0704(05)70384-5
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发表时间:
1998-01-01
影响因子:
4.3
通讯作者:
Cunha, BA
Cunha, BA
中科院分区:
医学2区
文献类型:
--
作者:
Cunha, BA

文献摘要

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社区获得性肺炎(CAP)在高龄患者中可能是严重的,在肝/肾功能不全、心肺疾病或宿主防御受损的患者中可能具有临床意义。轻度、中重度和重度CAP的病原体相同。这些病原体决定预后、并发症和治疗持续时间。经验性抗生素治疗应基于可能的病原体,而不是疾病的严重程度,因为疾病的严重程度会影响抗生素的效力,而不是所选择的抗生素谱。
Community-acquired pneumonia (CAP) is likely to be severe in the very elderly, and clinically significant in these with hepatic/renal insufficiency, cardiopulmonary disease, or, impaired host defenses. Pathogens in mild, moderately severe, and severe CAP are the same. These pathogens determine prognosis, complications, and duration of therapy. Empiric antimocrobial therapy should be based on likely pathogens, not severity of illness which affects the potency but not spectrum of antibiotic selected.