Relationship between mechanical thresholds and limb use in dogs with coxofemoral joint oa-associated pain and the modulating effects of pain alleviation from total hip replacement on mechanical thresholds.

Relationship between mechanical thresholds and limb use in dogs with coxofemoral joint oa-associated pain and the modulating effects of pain alleviation from total hip replacement on mechanical thresholds.
复制标题

患有髋股关节 OA 相关疼痛的狗的机械阈值和肢体使用之间的关系以及全髋关节置换术缓解疼痛对机械阈值的调节作用。

DOI：
10.1111/j.1532-950x.2014.12160.x
复制
发表时间：
2014
期刊：
Veterinary surgery : VS
影响因子：
--
通讯作者：
B. Lascelles
B. Lascelles
中科院分区：
--
文献类型：
--
作者：
A. Tomas;D. Marcellin;S. Roe;A. Motsinger;B. Lascelles

文献摘要

被引文献

相似文献

目标 比较单侧全髋关节置换术（THR）前犬骨盆肢体之间的von Frey机械定量感觉阈值（mQSTvF）;将地面反作用力（GRF）与mQSTvF相关联;评估THR手术后mQSTvF的变化。 研究设计 前瞻性临床研究。 动物 犬（n = 44）。 方法 在单侧THR之前和之后3、6和12个月，评价了使用压敏走道测量的mQSTvF和GRF。测量记录从受影响的（手术）骨盆肢（APL）和非手术骨盆肢（NPL）。采用随机效应分析和前向逐步线性回归模型评价手术后时间和患者因素对mQSTvF阈值的影响。 结果 mQSTvF数据与年龄、体重或GRF变量之间无显著相关性。在APL和NPL测量的术前mQSTvF没有差异（P = .909）。12个月后，NPL（P = 0.047）和APL（P = 0.001）的mQSTvF阈值显著增加。除时间外，APL mQSTvF值还受性别（雄性较高，P = .010）和身体状况评分（较瘦犬较高，P = .035）的显著影响，NPL mQSTvF值受性别影响（P = .038）。 结论 成功的单侧THR导致12个月后中枢敏感性降低。
OBJECTIVES To compare von Frey mechanical quantitative sensory thresholds (mQSTvF ) between pelvic limbs in dogs before unilateral total hip replacement (THR) surgery; to correlate ground reaction forces (GRF) with mQSTvF ; to assess changes in mQSTvF after THR surgery. STUDY DESIGN Prospective clinical study. ANIMALS Dogs (n = 44). METHODS mQSTvF and GRF measured using a pressure sensitive walkway were evaluated before, and 3, 6, and 12 months after, unilateral THR. Measurements were recorded from the affected (operated) pelvic limb (APL) and the non-operated pelvic limb (NPL). Random effects analysis and forwards stepwise linear regression models were used to evaluate the influence of time since surgery and patient factors on mQSTvF thresholds. RESULTS There were no significant correlations between mQSTvF data and age, bodyweight or the GRF variables. Preoperative mQSTvF measured at the APL and NPL did not differ (P = .909). mQSTvF thresholds increased significantly after 12 months in NPL (P = .047) and APL (P = .001). In addition to time, APL mQSTvF values were significantly affected by sex (higher in males, P = .010) and body condition score (higher in leaner dogs, P = .035) and NPL mQSTvF values by sex (P = .038). CONCLUSION Successful unilateral THR results in decreased central sensitization after 12 months.