Prevalence and burden based study in women
Prevalence and burden based study in women
复制标题
DOI：
10.1053/j.gastro.2005.04.006
复制
发表时间：
2005-07-01
期刊：
影响因子：
29.4
通讯作者：
Melton, LJ
中科院分区：
文献类型：
--
作者：
Bharucha, AE;Zinsmeister, AR;Melton, LJ
背景与目的：大便失禁（FI）的流行病学尚不完全清楚。我们报告了社区女性FI的患病率、临床谱、就医行为和生活质量。研究方法：问卷邮寄给明尼苏达州奥姆斯特德县5300名年龄分层随机抽样的妇女，这些妇女由罗切斯特流行病学项目确定。症状的严重程度进行了评估，并对生活质量的影响进行了评估，在过去的一年中有任何FI的受试者。FI的患病率是根据2000年美国白色女性人群的直接年龄调整计算的。结果：5300名妇女中有2800名（53%）对调查作出了回应。在过去一年中，FI的总体年龄调整患病率为12.1/100（95%置信区间，11.0-13.1）。患病率随着年龄的增长而增加，从每100人中有7人（第三个十年）增加到22人（第六个十年），此后保持稳定。症状为轻度（45%）、中度（50%）或重度（5%），症状严重程度与FI对QOL和医生咨询行为的影响有关。轻度、中度和重度症状对≥ 1个QOL领域的中度至重度影响分别为6%、35%和82%，而在过去一年中，轻度、中度和重度FI分别为5%、10%和48%。结论：人群中超过1/10的成年女性患有FI;几乎1/15患有中度至重度FI。FI显着影响生活质量，并提示医疗保健利用率主要是在中度至重度症状的妇女。
Background & Aims: The epidemiology of fecal incontinence (FI) is incompletely understood. We report the prevalence, clinical spectrum, health care-seeking behavior, and quality of life (QOL) in community women with FI. Methods: A questionnaire was mailed to an age-stratified random sample of 5300 Olmsted County, Minnesota, women identified by the Rochester Epidemiology Project. Symptom severity was assessed by a validated scale, and impact on QOL was evaluated for subjects who had any FI during the past year. The prevalence of FI was calculated with direct age adjustment to the 2000 US white female population. Results: Altogether, 2800 of 5300 women (53%) responded to the survey. The overall age-adjusted prevalence of FI in the past year was 12.1 per 100 (95% confidence interval, 11.0-13.1). The prevalence increased with age from 7 (third decade) to 22 (sixth decade) per 100 and was steady thereafter. Symptoms were mild (45%), moderate (50%), or severe (5%), and symptom severity was related to the impact of FI on QOL and physician-consuiting behavior. Moderate to severe impact on >= 1 domain of QOL was reported by 6% with mild, 35% with moderate, and 82% with severe symptoms, whereas 5% with mild, 10% with moderate, and 48% with severe FI had consulted a physician for FI in the past year. Conclusions: More than 1 of 10 adult women in the population have FI; almost 1 of 15 have moderate to severe FI. FI significantly impacts QOL and prompts health care utilization predominantly in women with moderate to severe symptoms.