Grammatical processing in schizophrenia: evidence from morphology.
Grammatical processing in schizophrenia: evidence from morphology.
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精神分裂症的语法处理：来自形态学的证据。
DOI：
10.1016/j.neuropsychologia.2009.09.012
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发表时间：
2010
期刊：
影响因子：
2.6
通讯作者：
Ullman,MichaelT
中科院分区：
文献类型：
--
作者：
Walenski,Matthew;Weickert,ThomasW;Maloof,ChristopherJ;Ullman,MichaelT
患有精神分裂症等精神疾病的患者通常会出现语言障碍。在这里，我们使用深入研究且相对容易理解的语言范式来研究精神分裂症中的语言，重点关注屈折形态。精神分裂症患者 (n = 43) 和年龄匹配的健康对照受试者 (n = 42) 被要求说出规则 (slip)、不规则 (swim) 和新颖 (plag) 英语动词的过去时态。在控制许多主题和项目特定因素（例如智商、语音复杂性）的情况下，患者在常规和新颖（滑倒、插曲）方面受到损害，而不规则（游动）相对较少。此外，患者的思维障碍分数显着预测了他们在常规和新颖（但不是不规则）过去时态生产中的表现。研究结果支持精神分裂症存在语法缺陷，词汇记忆相对较少，并表明思维障碍可能与该疾病的语法障碍有关。
Patients with psychiatric disorders such as schizophrenia commonly present with impaired language. Here we investigate language in schizophrenia with a focus on inflectional morphology, using an intensively studied and relatively well-understood linguistic paradigm. Patients with schizophrenia (n=43) and age-matched healthy control subjects (n=42) were asked to produce past tenses of regular (slip), irregular (swim), and novel (plag) English verbs. Patients were impaired at regulars and novels (slipped, plagged), with relative sparing of irregulars (swam), controlling for numerous subject- and item-specific factors (e.g., IQ, phonological complexity). Additionally, patients’ thought-disorder scores significantly predicted their performance at regular and novel (but not irregular) past-tense production. The results support grammatical deficits in schizophrenia, with a relative sparing of lexical memory, and suggest that thought disorder may be linked with grammatical impairments in the disorder.