Lower urinary tract symptoms in women with irritable bowel syndrome
Lower urinary tract symptoms in women with irritable bowel syndrome
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DOI：
10.1111/j.1442-2042.2009.02442.x
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发表时间：
2010-02-01
影响因子：
2.6
通讯作者：
Huang, Kuo-How
中科院分区：
文献类型：
--
作者：
Guo, Ya-Jun;Ho, Chen-Hsun;Huang, Kuo-How
目的：调查肠易激综合征（IBS）女性的下尿路症状（LUTS），并评估与这些患者精神疾病发病相关的危险因素。方法：研究组包括 52 名诊断为 IBS 的女性患者。 55 名没有胃肠道症状的女性被用作对照。使用美国泌尿外科协会症状指数问卷评估 LUTS。使用包含 12 项的中国健康调查问卷来评估精神疾病发病率。进行多元逻辑回归分析以确定与 IBS 患者精神疾病发病相关的危险因素。结果：两组之间的任何人口统计学变量均无显着差异。 IBS 患者最常见的 LUTS 是贮积症状。这些患者的尿频、夜尿、急迫性尿失禁评分显着较高，最大尿流量较低，排尿量较低（P < 0.05）。此外，IBS 患者的储存和总美国泌尿协会症状指数问卷评分也显着较高（P < 0.05）。 IBS 患者精神疾病患病率为 28.8%，显着高于对照组（20%）。储尿症状评分（比值比：1.518；95%置信区间：1.17-1.96；P = 0.002）与精神疾病发病率显着相关。 结论：LUTS在IBS患者中很常见，对其精神状态有负面影响。医疗保健提供者应该意识到 LUTS 对这些患者的心理后果。
Objectives:To investigate lower urinary tract symptoms (LUTS) in women with irritable bowel syndrome (IBS) and to evaluate risk factors associated with the psychiatric morbidity of these patients.Methods:The study group included 52 female patients with a diagnosis of IBS. Fifty-five women without gastrointestinal symptoms were used as controls. LUTS were evaluated using the American Urological Association Symptom Index questionnaire. Psychiatric morbidity was evaluated using a 12-item version of the Chinese Health Questionnaire. Multiple logistic regression analysis was performed to identify the risk factors associated with psychiatric morbidity in IBS patients.Results:There were no significant differences between the two groups in any of the demographic variables. The most common LUTS in patients with IBS were storage symptoms. These patients had significantly higher scores of frequency, nocturia, urge incontinence, lower maximal flow rate and lower voiding volume (P < 0.05). In addition, significantly higher storage and total American Urological Association Symptom Index questionnaire scores were also noted in IBS patients (P < 0.05). The prevalence of psychiatric morbidity in IBS patients was 28.8%, which was significantly higher than in the control group (20%). The urinary storage symptom score (odds ratio: 1.518; 95% confidence interval: 1.17-1.96; P = 0.002) was significantly correlated with psychiatric morbidity.Conclusions:LUTS are common in IBS patients and have a negative impact on their psychiatric status. Healthcare providers should be aware of the psychological consequences of LUTS in these patients.