Periconception window: advising the pregnancy-planning couple.
Periconception window: advising the pregnancy-planning couple.
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DOI：
10.1016/j.fertnstert.2007.12.043
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发表时间：
2008-02-01
影响因子：
6.7
通讯作者：
Handal, Alexis
中科院分区：
文献类型：
--
作者：
Louis, Germaine M B;Cooney, Maureen A;Handal, Alexis
目的：探讨受孕周围窗作为暴露的关键窗的重要性。回顾与健康孕周行为相关的经验数据。设计：文献综述。结论：人类生殖是一个夫妻依赖的过程。最近的文献强调，妊娠期是影响生长和发育的一个关键的暴露窗口。在给计划怀孕的夫妇提供建议时，最重要的是夫妇们知道生育窗口的时间，以确保性交发生在怀孕概率最大的日子。许多女性在试图怀孕时采取了更健康的生活方式，通常是戒烟、吃得更健康或服用维生素。然而，关于哪些环境暴露或行为是安全的或不安全的，缺乏前瞻性研究的实证数据。值得注意的是，没有关于男性伴侣暴露或行为对夫妇繁殖力和生育力的影响的数据。随着我们提高确定受孕时间的能力，我们应该能够更好地建议计划怀孕的夫妇。
OBJECTIVE: To discuss the importance of the periconceptional window with regard to being a critical window of exposure. To review the empirical data related to healthy periconceptional behaviors.DESIGN: Literature review.CONCLUSION(S): Human reproduction is a couple-dependent process. Recent literature has highlighted that the periconceptional time period is a critical window of exposure that can impact growth and development. In advising the pregnancy-planning couple, it is of paramount importance that couples have knowledge of the timing of the fertile window to ensure that intercourse occurs on days with the maximum probability of pregnancy. Many women adopt healthier lifestyles while trying to conceive, often quitting smoking, eating healthier or taking vitamins. However, there is a lack of empirical data from prospective studies regarding which environmental exposures or behaviors are or are not safe. Noticeably absent are data regarding the effect of male partners' exposures or behaviors on couple fecundity and fertility. As we improve our ability to pinpoint the timing of conception, we should be able to better advise couples planning pregnancy.