High muscle blood flows are not attenuated by recruitment of additional muscle mass.
High muscle blood flows are not attenuated by recruitment of additional muscle mass.
复制标题
高肌肉血流量不会因补充额外的肌肉质量而减弱。
DOI：
10.1152/ajpheart.1995.269.5.h1545
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发表时间：
1995
期刊：
影响因子：
--
通讯作者：
Wagner,PD
中科院分区：
文献类型：
--
作者：
Richardson,RS;Kennedy,B;Knight,DR;Wagner,PD
最近的研究表明，单腿膝关节伸肌（KE）运动elevens高质量比血流量（Q），如果增加到最大值，在额外的肌肉招募的存在下，将很快超过心脏的泵送能力和血压会下降。因此，增量KE锻炼提供了确定强度的机会，如果有的话，在涉及显著更大的肌肉质量的增量锻炼期间，四头肌肌肉血流动力学改变。在增量KE运动期间测量腿部Q，并在训练受试者（n = 5）中再次叠加增量双腿膝伸肌运动与增量手臂曲柄（A+L）。腿部Q和血管传导性（VC）随工作率（WR）增加而增加，达到高水平[KE和A+L运动的Q分别为385.7 +/- 26和342.3 +/- 15 ml.min-1.100 g-1;最大WR（WR max）90%时的VC = 79 +/- 5和75 +/- 6 ml.min-1。但在KE和A + L运动中Q/WR和VC/WR关系无显著差异。四头肌的最大耗氧量（VO 2 max）和VO 2 max/WR关系也不受招募的额外肌肉质量的影响。尽管在A+L运动中，90%和100%的WRmax时股静脉去甲肾上腺素（NE）净流出量显著更大（A+L和KE运动的WRmax分别为4，216 +/-1，601和901 +/- 99 ng/ml; P < 0.05），但腿部Q继续随WR线性上升。（250字处删节）
Recent studies have demonstrated that single-leg knee extensor (KE) exercise elicits high mass-specific blood flow (Q) which, if incremented toward maximum, in the presence of additional muscle recruitment would soon outstrip the heart's pumping capacity and blood pressure would fall. Thus incremental KE exercise provides the opportunity to determine the intensity at which, if at all, quadriceps muscle hemodynamics are altered during incremental exercise that involves a substantially greater muscle mass. Leg Q was measured during incremental KE exercise and again with superimposed incremental two-legged knee extensor exercise with incremental arm cranking (A+L) in trained subjects (n = 5). Leg Q and vascular conductance (VC) increased with work rate (WR) to reach high levels [Q = 385.7 +/- 26 and 342.3 +/- 15 ml.min-1.100 g-1 for KE and A+L exercise, respectively; VC at 90% of maximum WR (WRmax) = 79 +/- 5 and 75 +/- 6 ml.min-1. mmHg-1 for KE and A+L exercise, respectively], but the Q/WR and VC/WR relationships in KE and A+L exercise were not different. Maximum O2 consumption (VO2max) and the VO2max/WR relationship of the quadriceps were also unaffected by the additional muscle mass recruited. Despite a significantly greater net femoral venous norepinephrine (NE) outflow at both 90 and 100% of WRmax in A+L exercise (WRmax = 4,216 +/- 1,601 and 901 +/- 99 ng/ml for A+L and KE exercise, respectively; P < 0.05), leg Q continued to rise linearly with WR.(ABSTRACT TRUNCATED AT 250 WORDS)