Factors associated with health-related quality of life in papillary thyroid microcarcinoma patients undergoing radiofrequency ablation: a cross-sectional prevalence study
Factors associated with health-related quality of life in papillary thyroid microcarcinoma patients undergoing radiofrequency ablation: a cross-sectional prevalence study
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接受射频消融的甲状腺微小乳头状癌患者健康相关生活质量的相关因素：横断面患病率研究
DOI：
10.1080/02656736.2020.1812738
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发表时间：
2020-01
影响因子：
3.1
通讯作者：
Luo Yukun
中科院分区：
文献类型：
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作者：
Lan Yu;Jin Zhuang;Zhang Yan;Song Qing;Xiao Jing;Yan Lin;Zhu Yaqiong;Zhang Mingbo;Luo Yukun
摘要目的探讨甲状腺乳头状微小癌（PTMC）射频消融术（RFA）患者的人口学特征、临床症状和对疾病进展的恐惧因素与健康相关生活质量（HRQoL）的相关性。方法2019年10月至2020年3月，123例PTMC幸存者接受RFA治疗。收集人口统计学、临床症状和对疾病进展的恐惧数据。采用SF-36、THYCA-QoL和FoP-Q-SF评价患者的HRQoL、临床症状和对疾病进展的恐惧。采用多变量回归模型评价自变量与HRQoL变量之间的相关性。结果PCS组和MCS组的HRQoL自评得分分别为81.17 ± 15.48和73.40 ± 18.03。多元线性回归模型显示，女性患者的PCS较差的相关因素是依赖性的，神经肌肉和咽喉/口腔症状，对疾病进展的恐惧;心理障碍，咽喉/口腔症状，无法集中注意力与MCS评分较差相关。与HRQoL较差（PCS和MCS）最密切相关的条件是对身体健康的恐惧。结论PTMC幸存者在PCS和MCS中HRQoL评分显著降低的相关因素包括女性、神经肌肉和咽喉/口腔症状、心理障碍、注意力不集中和对自身身体健康的恐惧。识别、管理和预防这些因素对于改善患者的HRQoL至关重要。
Abstract Purpose To explore the association of demographic characteristics, clinical symptoms and the fear of the disease progression factors with the physical and mental summary components of the health-related of life (HRQoL) of the papillary thyroid microcarcinoma (PTMC) patients undergoing radiofrequency ablation (RFA). Methods 123 PTMC survivors undergoing RFA were enrolled in this study from October 2019 to March 2020. Demographic, clinical symptoms and the fear of the disease progression data were collected. SF-36, THYCA-QoL and FoP-Q-SF were used to evaluate the HRQoL of patients, clinical symptoms and the fear of disease progression. A multivariate regression model was performed to evaluate the association between the independent variable and the HRQoL variable. Results The average self-reported HRQoL score was 81.17 ± 15.48 for the PCS and 73.40 ± 18.03 for the MCS. The multivariate linear regression model shows that the factors related to a poorer PCS were dependent for the female patients, the symptoms of neuromuscular and the throat/mouth, the fear of disease progression; the psychological disorder, symptoms of throat/mouth, inability to concentrate were related to worse scores for the MCS. The condition that was most strongly related to a poorer HRQoL (in both PCS and MCS) was the fear of their physical health. Conclusions The factors related to significantly worse HRQoL scores across PCS and MCS for PTMC survivors include the female gender, the symptoms of neuromuscular and the throat/mouth, the psychological disorder, inability to concentrate, and the fear of their own physical health. Identification, management, and prevention of these factors are critical to improving the HRQoL of patients.
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DOI：
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发表时间：
2017
期刊：
--
影响因子：
--
作者：
Kaliszewski;Diakowska;Strutyńska-Karpińska;Wojtczak;Domosławski;Balcerzak
通讯作者：
Kaliszewski;Diakowska;Strutyńska-Karpińska;Wojtczak;Domosławski;Balcerzak
DOI：
10.1891/9780826121646.0002
发表时间：
2018-09
期刊：
Cancer Rehabilitation
影响因子：
--
作者：
K. Miller;R. Siegel;R. Khan;A. Jemal
通讯作者：
K. Miller;R. Siegel;R. Khan;A. Jemal
影响因子：
11.9
作者：
Mari Sengoku;H. Murata;T. Kawahara;K. Imamura;K. Nakagome
通讯作者：
Mari Sengoku;H. Murata;T. Kawahara;K. Imamura;K. Nakagome
影响因子：
3.7
作者：
Jegerlehner S;Bulliard JL;Aujesky D;Rodondi N;Germann S;Konzelmann I;Chiolero A;NICER Working Group
通讯作者：
NICER Working Group
影响因子：
3.1
作者：
Hedman, Christel;Djarv, Therese;Lundgren, Catharina Ihre
通讯作者：
Lundgren, Catharina Ihre