The effects of cognitive impairment on mortality among hospitalized patients with heart failure

The effects of cognitive impairment on mortality among hospitalized patients with heart failure
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DOI:
10.1016/s0002-9343(03)00264-x
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发表时间:
2003-08-01
影响因子:
5.9
通讯作者:
Bernabei, R
Bernabei, R
中科院分区:
医学2区
文献类型:
--
作者:
Zuccalà, G;Pedone, C;Bernabei, R

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目的:认知障碍是老年心力衰竭患者中一种常见的、潜在可逆的疾病。由于脑代谢异常与年轻晚期心力衰竭患者的生存率降低有关,我们评估了认知障碍对老年心力衰竭患者生存率的影响。方法:对意大利81家医院因心力衰竭入院的1113例患者(平均[+/- SD]年龄,78 +/- 9岁)的认知功能障碍与住院死亡率之间的关系进行评估。对参与同一研究的968例心力衰竭患者(年龄76岁,10岁)的一年死亡率进行了评估。认知障碍被定义为霍金森简略智力测验分数
PURPOSE: Cognitive impairment is a common, potentially reversible condition among older patients with heart failure. Because cerebral metabolic abnormalities have been associated with reduced survival in younger patients with advanced heart failure, we assessed the effect of cognitive impairment on the survival of older patients with heart failure.METHODS: The association between cognitive dysfunction and in-hospital mortality was assessed in 1113 patients (mean [+/- SD] age, 78 +/- 9 years) who had been admitted for heart failure to 81 hospitals throughout Italy. One-year mortality was assessed in 968 patients with heart failure (age, 76 10 years) participating in the same study. Cognitive impairment was defined as a Hodkinson Abbreviated Mental Test score