t Immediate Neural Plasticity Shapes Motor Performance
t Immediate Neural Plasticity Shapes Motor Performance
复制标题
直接神经可塑性塑造运动表现
作者：
tMichael C. Dorris;M. Paré;D. Munoz
运动技能的巩固需要神经系统的长期改变。在大多数情况下，经过训练和长期适应后，运动系统的可塑性已被记录下来。然而，还没有证据表明与动态环境交互所需的运动行为的快速适应相关的直接神经变化。为了解决这个问题，我们探索了恒河猴的性能（反应时间）变化，恒河猴对两种视觉刺激之一执行扫视眼动，同时监测上丘神经元的准备活动，上丘是接近运动输出的结构。与在人类手动反应中观察到的良好的顺序效应类似，每只猴子对以顺序模式组织的目标位置表现出反应时间，随着前面的每次重复运动逐渐变短，随着前面的每次非重复运动逐渐变长。这种性能修改的顺序模式与扫视目标呈现之前上丘神经元准备活动的一致变化相关。这些数据表明，神经特性是由与使用相关的经验以与运动行为的渐进适应一致的方式不断塑造的。
The consolidation of motor skills necessitates long-lasting changes in the nervous system. For the most part, plasticity has been documented in motor systems after training and long-term adaptation. However, there has been no demonstration of immediate neural changes associated with the rapid adaptation of motor behavior required to interact with a dynamic environment. To address this issue, we explored the changes in performance (reaction time) of rhesus monkeys that executed saccadic eye movements to one of two visual stimuli while monitoring the preparatory activity of neurons in the superior colliculus, a structure close to the motor output. Similar to the well established sequential effects observed in human manual responses, each monkey displayed reaction times to target locations that were organized in a sequential pattern, becoming progressively shorter with each preceding repeated movement and longer with each preceding nonrepeated movement. This sequential pattern of performance modification was associated with concordant changes in the preparatory activity of superior colliculus neurons in advance of the saccadic target presentation. These data indicate that neural properties are continuously shaped by use-related experience in a manner consistent with the progressive adaptation of motor behavior.
DOI：
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发表时间：
1989
期刊：
Reviews of oculomotor research
影响因子：
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作者：
D. Sparks;R. Hartwich-Young
通讯作者：
D. Sparks;R. Hartwich-Young