Effect of Partition of Photo-initiator Components and Addition of Iodonium Salt on the Photopolymerization of Phase-Separated Dental Adhesive.
Effect of Partition of Photo-initiator Components and Addition of Iodonium Salt on the Photopolymerization of Phase-Separated Dental Adhesive.
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DOI：
10.1007/s11837-016-1816-2
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发表时间：
2016-04
期刊：
影响因子：
--
通讯作者：
Spencer P
中科院分区：
文献类型：
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作者：
Abedin F;Ye Q;Song L;Ge X;Camarda K;Spencer P
研究了一种模型牙科粘合剂物理分离的疏水相和富亲水相的聚合动力学。由含有甲基丙烯酸2-羟乙酯(HEMA)和双酚A甘油酸二甲酯(BisGMA)的纯树脂按45：55(wt/wt)的比例制备了两相。合成了几种常用的光引发剂组合，如樟子酚(CQ)、4-二甲氨基苯甲酸乙酯(EDMAB)、甲基丙烯酸2-(二甲氨基)乙酯(DMAEMA)和六氟磷酸二苯碘(DPIHP)。为了得到这两种相，在纯树脂中加入了33wt%的氧化重氢(D2O)。这一D2O的量超过了树脂的相容极限。用高效液相色谱法测定了光引发体系中各组分在两相中的浓度。当与CQ结合时，与EDMAB相比，DMAEMA作为共引发剂的效率较低。将DPIHP作为第三组分加入到CQ/EDMAB或CQ/DMAEMA光引发体系中，可以在疏水和亲水两种相中获得相似的性能。碘盐的加入显著促进了富水相的光聚合；当配方中不含碘盐时，富水相表现出极差的聚合性能。EDMAB在富水相中的分配浓度明显低于DMAEMA或DPIHP。这项研究表明，需要结合疏水/亲水光敏剂和添加碘盐来改善牙科粘合剂中富水相的聚合。
The polymerization kinetics of physically separated hydrophobic- and hydrophilic-rich phases of a model dental adhesive have been investigated. The two phases were prepared from neat resin containing 2-hydroxyethyl methacrylate (HEMA) and bisphenol A glycerolate dimethacrylate (BisGMA) in the ratio of 45:55 (wt/wt). Neat resins containing various combinations of popular photo-initiating compounds, e.g., camphoquinone (CQ), ethyl 4-(dimethylamino)benzoate (EDMAB), 2-(dimethylamino)ethyl methacrylate (DMAEMA) and diphenyliodonium hexafluorophosphate (DPIHP) were prepared. To obtain the two phases 33 wt% of deuterium oxide (D2O) was added to the neat resins. This amount of D2O exceeded the miscibility limit for the resins. The concentration of each component of the photo-initiating system in the two phases was quantified by HPLC. When combined with CQ, DMAEMA is less efficient as a co-initiator compared to EDMAB. The addition of DPIHP as the third component into either CQ/EDMAB or CQ/DMAEMA photo-initiating systems leads to comparable performance in both the hydrophobic- and hydrophilic-rich phases. The addition of the iodonium salt significantly improved the photopolymerization of the hydrophilic-rich phase; the hydrophilic-rich phase exhibited extremely poor polymerization when the iodonium salt was not included in the formulation. The partition concentration of EDMAB in the hydrophilic-rich phase was significantly lower than that of DMAEMA or DPIHP. This study indicates the need for a combination of hydrophobic/hydrophilic photosensitizer and addition of iodonium salt to improve polymerization within the hydrophilic-rich phase of the dental adhesive.