Changes in Androstenedione, Testosterone and Protein Metabolism as a Result of Exercise
Changes in Androstenedione, Testosterone and Protein Metabolism as a Result of Exercise
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运动引起的雄烯二酮、睾酮和蛋白质代谢的变化
DOI：
10.3181/00379727-158-40260
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发表时间：
1978
影响因子：
--
通讯作者：
Thomas M. Louis
中科院分区：
文献类型：
--
作者：
G. Dohm;Thomas M. Louis
摘要 在雄性、雌性和去势雄性大鼠中研究了耐力训练对尿素排泄和血浆雄激素浓度的影响。训练增加了雄性大鼠的尿素排泄，但没有增加雌性大鼠的尿素排泄。雄性大鼠的去势使尿素排泄增加到与训练过的大鼠中观察到的水平相同，但训练并没有进一步增加尿素排泄。受过训练的大鼠的睾酮水平低于未经训练的大鼠。在经过训练的大鼠中，运动后睾酮水平立即略有增加（P > 0.05），但运动后 6 小时睾酮浓度显着降低（P < 0.05）。在一次力竭的运动后，血浆睾酮也显着降低。这些结果表明，血浆雄激素水平的变化可能是我们在训练过的大鼠中观察到的尿素排泄增加的原因。
Summary The effects of endurance training on urea excretion and plasma androgen concentrations were investigated in male, female, and castrated male rats. Training increased urea excretion in male rats but not in female rats. Castration of male rats increased urea excretion to levels like those observed in trained rats and training did not further increase urea excretion. The level of testosterone in trained rats was lower than that of untrained rats. In trained rats there was a slight (P > 0.05) increase in testosterone immediately after exercise but the concentration of testosterone was significantly (P < 0.05) lowered 6 hr after the exercise bout. Plasma testosterone was also significantly lowered after an exhaustive exercise run. These results suggest that an alteration in plasma androgen levels may be responsible for the increased urea excretion that we observed in trained rats.