Detecting impairment associated with cannabis with and without alcohol on the Standardized Field Sobriety Tests
Detecting impairment associated with cannabis with and without alcohol on the Standardized Field Sobriety Tests
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DOI：
10.1007/s00213-012-2787-9
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发表时间：
2012-12-01
影响因子：
3.4
通讯作者：
Stough, Con
中科院分区：
文献类型：
--
作者：
Downey, Luke A.;King, Rebecca;Stough, Con
大麻和酒精是娱乐用户中最受欢迎的药物，在受伤和死亡的司机中最普遍。标准化现场清醒度测试（SFST）通常用于建立损害由于药物和酒精，但有限的经验证据存在这些药物对SFST performance.The样本包括80个人（31名女性，49名男性）的综合影响。年龄范围为21 - 35岁（M = 26.5，SD = 5）。40名参与者（15名女性; 25名男性）参加了低酒精条件（BAC，<0.05%），40名参与者（16名女性; 24名男性）参加了高酒精条件（BAC，> 0.05%）。对于研究的每个部分，给予两种水平的匕首9-四氢大麻酚（THC）（1.8%和3% THC）或与酒精组合的匹配安慰剂香烟（0% THC）。在给药后30分钟评估SFST表现。当低酒精和低THC一起给药时，确定了SFST表现的许多显著差异，其中28%的样品未通过测试（当包括头部运动和抽搐体征时）。当高剂量的酒精与低剂量的四氢大麻酚同时服用时，38%的样本未能通过测试，而当高剂量的酒精与高剂量的四氢大麻酚同时服用时，35%的样本也未能通过测试。目前的结果显示，在没有任何驾驶障碍或生理指标的情况下，财经事务及库务局局长在识别药物消耗方面的能力有限。
Cannabis and alcohol are the most popular drugs amongst recreational users and most prevalent in injured and deceased drivers. The Standardized Field Sobriety Tests (SFST) are commonly used to establish impairment due to drugs and alcohol, but limited empirical evidence exists concerning the combined effects of these drugs on SFST performance.The sample comprised 80 individuals (31 females; 49 males). Age ranged between 21 and 35 years (M = 26.5, SD = 5). Forty participants (15 females; 25 males) took part in the low alcohol condition (BAC, < 0.05 %), and 40 participants (16 females; 24 males), took part in the high alcohol condition (BAC, > 0.05 %). For each part of the study, two levels of a dagger 9-tetrahydrocannabinol (THC) were administered (1.8 and 3 % THC) or a matching placebo cigarette (0 % THC) in combination with alcohol. Performance on the SFST was assessed 30 min post-dosing.A number of significant differences in SFST performance were identified with 28 % of the sample failing the test (when the head movement and jerks sign was included) when low alcohol and low THC were administered together. When a higher dose of alcohol was administered with a low dose of THC, 38 % of the sample failed the test, and 35 % also failed when the high dose of alcohol was combined with a higher dose of THC.The current results highlight the limited ability of the SFST to identify drug consumption in the absence of any evidence of driving impairment or physiological indicators.