Early neuron differentiation in the mouse olfactory bulb. II. Electron microscopy
Early neuron differentiation in the mouse olfactory bulb. II. Electron microscopy
复制标题
小鼠嗅球的早期神经元分化。
DOI：
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发表时间：
1972
期刊：
影响因子：
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通讯作者：
J. Hinds
中科院分区：
文献类型：
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作者：
J. Hinds
Differentiating mitral cells were followed in serial section analysis of mouse embryos from day 12 of gestation (E12) to E14. Animals at E11 and E15 were also examined. Olfactory nerve axons reach the presumptive olfactory bulb at E12 and many penetrate deeply into the intermediate (mantle) layer at this time. The first identified young neurons (postmitotic neuroblasts) were also seen at E12. Many had a tangential orientation, and they occurred only in the region where olfactory nerve axons were present. Olfactory nerve axons (and also mitral cell axons formed later) are characterized by numerous longitudinallyoriented microtubules and an extensive system of transversely and longitudinallyorinted cisternae of smooth endoplasmic reticulum (SER). Near the growing tips of olfactory nerve axons, the microtubules disappear and the SER becomes more extensive and irregular.
