Effects of moderate caffeine intake in athletes.
Effects of moderate caffeine intake in athletes.
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适量咖啡因摄入对运动员的影响。
DOI：
10.1016/j.ejim.2023.09.018
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发表时间：
2024
影响因子：
8
通讯作者：
Komici,Klara
中科院分区：
文献类型：
--
作者：
Mone,Pasquale;Guerra,Germano;Verderosa,Sofia;Santulli,Gaetano;Komici,Klara
咖啡因摄入会增加房性早搏 (PAC) 和室性早搏 (PVC) 的风险，因为咖啡因通过多巴胺和去甲肾上腺素产生拟交感神经作用 [1-3]。美国心脏病学会/美国心脏协会指南指出，咖啡因可导致室上性心律失常的发作，有额外心跳史的患者应避免摄入咖啡因[4]。先前的研究表明，长期饮用咖啡可降低心房颤动的风险，并且与老年人的异位无关[5, 6]。我们测试了适量咖啡摄入对这一人群的影响，以在年轻运动员中证实这些结果。这是一项针对在意大利坎波巴索莫利塞大学医学与健康科学系“安东尼奥·卡达雷利医院”运动与运动医学科接受临床评估的连续运动员的观察性研究。我们采用以下纳入标准：a) 年龄≥ 16 岁 b) 不服用常量营养素和/或膳食补充剂 c) 愿意参与本研究。我们收集了有关心血管危险因素、心律失常、高血压、哮喘和药物治疗的病史数据。我们为所有运动员登记了运动纪律，并根据运动类型和强度水平进行分类。我们没有在分析中纳入提及“卡布奇诺”和/或茶的受试者。我们评估了体重指数 (BMI)、静息收缩压和舒张压 (DBP) 以及基线心率。我们根据 SBP 和 DBP 差值计算脉压。所有参与者根据改良布鲁斯方案进行静息心电图和跑步机运动测试。使用跑步机Cosmed T150med和Omnia Quark CPET Cosmed 2019分析系统进行运动测试。在整个测试过程中持续使用 12 导联心电图记录系统（Quark T12X 无线）。我们在测试的每个阶段结束时测量了动脉血压（BP）。我们记录了有关预测最大心率（220 岁）、运动测试期间达到的最大心率、ST-T 修改以及存在的数据
Caffeine intake increases the risk of premature atrial contractions (PACs) and premature ventricular contractions (PVCs) because of its sympathomimetic effects via dopamine and norepinephrine [1-3]. The American College of Cardiology/American Heart Association guidelines stated that caffeine can drive the onset of supraventricular arrhythmias and should be avoided in patients with history of extra beats [4]. Previous investigations showed that chronic coffee consumption reduced the risk of atrial fibrillation and led no association with ectopy in older adults [5, 6]. We tested the effects of moderate coffee consumption in this population in order to confirm these results in young athletes. This is an observational study of consecutive athletes undergoing clinical evaluation in the Exercise and Sports Medicine Unit “Antonio Cardarelli Hospital”, Department of Medicine and Health Sciences, University of Molise, Campobasso, Italy. We applied the following inclusion criteria: a) age≥ 16 years b) taking no macronutrients and/or dietary supplements and c) willingness to participate in this study. We collected anamnestic data on cardiovascular risk factors, arrythmias, hypertension, asthma and medical treatment. We registered sport discipline for all athletes, with the classification based on the type of exercise and level of intensity. We did not include subjects which referred “cappuccino” and or tea in the analysis. We evaluated body Mass Index (BMI), resting systolic and diastolic blood pressure (SBP)(DBP), and baseline heart rate.We calculated pulse pressure from SBP and DBP difference. All participants performed a resting ECG and treadmill exercise testing according to the Modified Bruce Protocol. Treadmill Cosmed T150med and Omnia Quark CPET Cosmed 2019 analysis system were used for exercise testing. A 12 lead ECG recording system (Quark T12X wireless) was used continually throughout the test. We measured arterial blood pressure (BP) at the end of each stage of the test. We registered data regarding predicted maximal HR (220-age), maximal HR reached during exercise testing, ST-T modification and the presence of