PERIPHERAL VASCULAR REACTIVITY TO ANGIOTENSIN AND NORADRENALINE IN PREGNANT AND NON-PREGNANT WOMEN

PERIPHERAL VASCULAR REACTIVITY TO ANGIOTENSIN AND NORADRENALINE IN PREGNANT AND NON-PREGNANT WOMEN
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DOI:
10.1038/icb.1970.49
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发表时间:
1970-01-01
期刊:
AUSTRALIAN JOURNAL OF EXPERIMENTAL BIOLOGY AND MEDICAL SCIENCE
影响因子:
--
通讯作者:
LUMBERS, ER
LUMBERS, ER
中科院分区:
其他
文献类型:
--
作者:
LUMBERS, ER

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The hand vascular sensitivity to angiotensin is reduced in pregnant women as compared to non‐pregnant women. Since the hand vasculature retains a normal response to noradrenaline in pregnant women, this reduction in sensitivity to angiotensin is selective.Furthermore, the reduction in sensitivity to the pressor response to angiotensin seen in pregnant women must, in part, be due to a reduction in peripheral vascular sensitivity.Elevations in plasma renin activity, renin concentration and renin substrate level are associated with the reduction in sensitivity to angiotensin observed.