Droplet-based DNA purification in a magnetic lab-on-a-chip

Droplet-based DNA purification in a magnetic lab-on-a-chip
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DOI:
10.1002/anie.200503624
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发表时间:
2006-01-01
影响因子:
16.6
通讯作者:
Gijs, Martin A. M.
Gijs, Martin A. M.
中科院分区:
化学1区
文献类型:
--
作者:
Lehmann, Ulrike;Vandevyver, Caroline;Gijs, Martin A. M.

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合并、混合、分裂和运输,这些是用于芯片上基于液滴的DNA纯化的主要操作步骤(见图)。该系统能够通过使用液滴内的磁性微粒通过线圈矩阵的致动来从稀释的细胞样品中提取基因组材料。
Merge, Mix, Split and Transport, these are the main manipulation steps used for on-chip droplet-based DNA purification (see figure). The system is able to extract genomic material from dilute cell samples by using the actuation of magnetic microparticles within the droplets through a matrix of coils.