Glucocorticoids regulate expression of dihydrofolate reductase cDNA in mouse mammary tumour virus chimaeric plasmids
Glucocorticoids regulate expression of dihydrofolate reductase cDNA in mouse mammary tumour virus chimaeric plasmids
复制标题
糖皮质激素调节小鼠乳腺肿瘤病毒嵌合质粒中二氢叶酸还原酶cDNA的表达
作者：
F. Lee;R. Mulligan;P. Berg;G. Ringold
小鼠乳腺肿瘤病毒长末端重复序列和小鼠二氢叶酸还原酶 cDNA 之间的融合体已在 SV40 载体中构建。当这些质粒转移到受体细胞中时，二氢叶酸还原酶的产生受到糖皮质激素的调节。这些结果定义了病毒基因组的激素反应区域。
Fusions between the mouse mammary tumour virus long terminal repeat and a mouse dihydrofolate reductase cDNA have been constructed in a SV40 vector. When these plasmids are transferred into recipient cells, the production of dihydrofolate reductase is regulated by glucocorticoid hormones. These results define a hormonally responsive region of the viral genome.
DOI：
10.1073/pnas.77.7.4216
发表时间：
1980-01-01
期刊：
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES
影响因子：
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作者：
URLAUB, G;CHASIN, LA
通讯作者：
CHASIN, LA