Complicated grief symptoms in anxiety disorders: prevalence and associated impairment.
Complicated grief symptoms in anxiety disorders: prevalence and associated impairment.
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DOI：
10.1002/da.22093
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发表时间：
2013-12
影响因子：
7.4
通讯作者：
Simon, Naomi
中科院分区：
文献类型：
--
作者：
Marques, Luana;Bui, Eric;LeBlanc, Nicole;Porter, Eliora;Robinaugh, Donald;Dryman, M. Taylor;Nadal-Vicens, Mireya;Worthington, John;Simon, Naomi
先前的研究已经确定，在原发性CG患者中，共病性焦虑症的发生率很高。在本研究中，我们比较了丧亲者原发性焦虑障碍（AD）患者与健康对照者共病性CG的患病率。我们还研究了与AD共病性CG相关的损伤。参与者包括242名患有原发性AD诊断的丧偶成人（平均（SD）年龄= 41.5(13.1)，女性44.2%），包括广泛性焦虑障碍（GAD, n = 57）、恐慌障碍（PD, n = 49）、创伤后应激障碍（PTSD, n = 29）和广泛性社交焦虑障碍（GSAD, n = 107），以及155名没有当前DSM-IV轴I诊断的丧偶健康对照（平均（SD）年龄= 43.0(13.6)，女性51.0%）。使用19项复杂悲伤量表（ICG）测量CG症状，阈值CG定义为ICG评分≥30。分别用生活质量享受与满意度问卷（Q-LES-Q）和功能障碍范围量表（life - rift）评估生活质量和功能障碍。原发性ad患者的阈值CG症状率明显高于丧亲者（12.0% vs 0.65%; Fisher’s Exact P < 0.001）。与失去亲人的对照组相比，每个AD的阈值CG率显著升高。在调整了年龄、性别、教育程度和共病性抑郁症后，AD患者的阈值CG与较低的生活质量（β = - 0.140, P = 0.023）和较大的损害（β = 0.141, P = 0.035）相关。我们的研究结果表明阈值CG在患有原发性焦虑障碍的丧亲个体中具有临床相关性。对ad患者进行CG筛查是有必要的。
Previous research has identified high rates of comorbid anxiety disorders among individuals presenting with primary CG. In the present study, we examined the prevalence of comorbid CG in bereaved primary anxiety disorder (AD) patients compared to bereaved healthy controls. We also examined the impairment associated with comorbid CG in AD. Participants were 242 bereaved adults (mean (SD) age = 41.5 (13.1), 44.2% women) with a primary AD diagnosis, including generalized anxiety disorder (GAD; n = 57), panic disorder (PD; n = 49), posttraumatic stress disorder (PTSD; n = 29), and generalized social anxiety disorder (GSAD; n = 107), as well as 155 bereaved healthy controls with no current DSM-IV Axis I diagnosis (mean (SD) age = 43.0 (13.6), 51.0% women). CG symptoms were measured using the 19-item inventory of complicated grief (ICG), with threshold CG defined as an ICG score of ≥30. Quality of life and functional impairment were assessed with the Quality of Life Enjoyment and Satisfaction Questionnaire (Q-LES-Q) and the Range of Impaired Functioning Tool (LIFE-RIFT), respectively. Participants with primary ADs had significantly higher rates of threshold CG symptoms than bereaved controls (12.0% vs. 0.65%; Fisher’s Exact P < 0.001). Rates of threshold CG were significantly elevated for each AD when compared to bereaved controls. After adjustment for age, sex, education, and comorbid major depressive disorder, threshold CG was associated with lower quality of life (β = −0.140, P = 0.023) and greater impairment (β = 0.141, P = 0.035) among individuals with AD. Our findings suggest that threshold CG is of clinical relevance in bereaved individuals with a primary anxiety disorder. Screening for CG in patients with ADs may be warranted.
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影响因子：
17.7
作者：
Boelen, PA;van den Bout, J;de Keijser, J
通讯作者：
de Keijser, J
影响因子：
17.7
作者：
Shear, MK;Frank, E;Masters, S
通讯作者：
Masters, S
影响因子：
7.4
作者：
Shear, M. Katherine;Simon, Naomi;Wall, Melanie;Zisook, Sidney;Neimeyer, Robert;Duan, Naihua;Reynolds, Charles;Lebowitz, Barry;Sung, Sharon;Ghesquiere, Angela;Gorscak, Bonnie;Clayton, Paula;Ito, Masaya;Nakajima, Satomi;Konishi, Takako;Melhem, Nadine;Meert, Kathleen;Schiff, Miriam;O'Connor, Mary-Frances;First, Michael;Sareen, Jitender;Bolton, James;Skritskaya, Natalia;Mancini, Anthony D.;Keshaviah, Aparna
通讯作者：
Keshaviah, Aparna
影响因子：
15.8
作者：
Prigerson HG;Horowitz MJ;Jacobs SC;Parkes CM;Aslan M;Goodkin K;Raphael B;Marwit SJ;Wortman C;Neimeyer RA;Bonanno GA;Block SD;Kissane D;Boelen P;Maercker A;Litz BT;Johnson JG;First MB;Maciejewski PK
通讯作者：
Maciejewski PK
影响因子：
11.3
作者：
Golden, Ann-Marie J.;Dalgleish, Tim
通讯作者：
Dalgleish, Tim