Recent Developments in Negishi Cross-Coupling Reactions
Recent Developments in Negishi Cross-Coupling Reactions
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DOI：
10.1021/acscatal.5b02718
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发表时间：
2016-03-01
期刊：
影响因子：
12.9
通讯作者：
Knochel, Paul
中科院分区：
文献类型：
--
作者：
Haas, Diana;Hammann, Jeffrey M.;Knochel, Paul
本透视图描述了制备多官能锌有机金属化合物的一般方法及其在根岸交叉偶联反应中的应用。介绍了新配体和钯催化剂的最新进展。涉及Ni-，Cu-，Co-和Fe-催化的交叉偶联的相关根岸交叉偶联反应被覆盖。一系列锌有机金属化合物与新的有效催化剂相结合的可用性允许在通常温和的条件下与各种有机亲电试剂进行有效的交叉偶联反应。
This Perspective describes general methods for the preparation of polyfunctional zinc organometallics and their use in Negishi cross-coupling reactions. Recent advances including new ligands and palladium catalysts are described. Related Negishi cross-coupling reactions involving Ni-, Cu-, Co-, and Fe-catalyzed cross-couplings are covered. The availability of a range of zinc organometallics combined with new efficient catalysts allows for efficient cross coupling reactions with various organic electrophiles under usually mild conditions.