Pilot study of trigeminal nerve stimulation (TNS) for epilepsy: A proof-of-concept trial
Pilot study of trigeminal nerve stimulation (TNS) for epilepsy: A proof-of-concept trial
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DOI：
10.1111/j.1528-1167.2006.00594.x
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发表时间：
2006-07-01
期刊：
影响因子：
5.6
通讯作者：
Whitehurst, Todd
中科院分区：
文献类型：
--
作者：
DeGiorgio, Christopher M.;Shewmon, Alan;Whitehurst, Todd
三叉神经刺激（TNS）治疗癫痫的安全性和初步疗效在三叉神经眶下和眶上分支经皮刺激的初步可行性研究中进行了评价。TNS耐受性良好。完成≥ 3个月的7名受试者中有4名（57%）的癫痫发作频率降低≥ 50%。这项初步研究的结果支持进一步研究TNS治疗癫痫的安全性和有效性。
The safety and preliminary efficacy of trigeminal nerve stimulation (TNS) for epilepsy was evaluated in a pilot feasibility study of transcutaneous stimulation of the infraorbital and supraorbital branches of the trigeminal nerve. TNS was well tolerated. Four (57%) of seven subjects who completed >= 3 months experienced a >= 50% reduction in seizure frequency. The results of this pilot study support further investigation into the safety and efficacy of TNS for epilepsy.